Database of mammalian genes
Home

Home Search Browse Statistics User guide FAQs Links Questions Contribute Download


Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for MRPL23 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID6150
Official gene symbolMRPL23
Full namemitochondrial ribosomal protein L23
Aliases,FLJ45387,L23MRP,RPL23,RPL23L,
Gene summaryMammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. The gene is biallelically expressed, despite its location within a region of imprinted genes on chromosome 11. [provided by RefSeq]
LocationChromosome: 11   Locus: 11p15.5-p15.4
Gene position1968502 - 1977839  Map Viewer
Gene orientationplus
Gene size9338 bp
Gene sequence
OMIM ID600789