Entrez gene ID | | 6150 |
Official gene symbol | | MRPL23 |
Full name | | mitochondrial ribosomal protein L23 |
Aliases | | ,FLJ45387,L23MRP,RPL23,RPL23L, |
Gene summary | | Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. The gene is biallelically expressed, despite its location within a region of imprinted genes on chromosome 11. [provided by RefSeq] |
Location | | Chromosome: 11 Locus: 11p15.5-p15.4 |
Gene position | | 1968502 - 1977839 Map Viewer |
Gene orientation | | plus |
Gene size | | 9338 bp |
Gene sequence |
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OMIM ID | | 600789 |
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