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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for SAA1 (Homo sapiens) (Information is obtained from NCBI Gene database)

Entrez gene ID 6288 Official gene symbol SAA1 Full name serum amyloid A1 Aliases ,MGC111216,PIG4,SAA,SAA2,TP53I4, Gene summary This gene encodes a member of the serum amyloid A family of apolipoproteins. The encoded protein is a major acute phase protein that is highly expressed in response to inflammation and tissue injury. This protein also plays an important role in HDL metabolism and cholesterol homeostasis. High levels of this protein are associated with chronic inflammatory diseases including atherosclerosis, rheumatoid arthritis, Alzheimer's disease and Crohn s disease. This protein may also be a potential biomarker for certain tumors. Alternate splicing results in multiple transcript variants that encode the same protein. A pseudogene of this gene is found on chromosome 11. Location Chromosome: 11   Locus: 11p15.1 Gene position 18287808 - 18291524  Map Viewer Gene orientation plus Gene size 3717 bp Gene sequence >SAA1:18227808..18231524:Length=3717 GGCAGGGACCCGCAGCTCAGCTACAGCACAGATCAGGTGAGGAGCACACCAAGGAGTGAT TTTTAAAACTTACTCTGTTTTCTCTTTCCCAACAAGATTATCATTTCCTTTAAAAAAAAT AGTTATCCTGGGGCATACAGCCATACCATTCTGAAGGTGTCTTATCTCCTCTGATCTAGA GAGGTAAGCAGGGTCGGGCCTGGTAGTACTTGGATGGGAGAACACCTGGGAATACCAGGT GCTAAAGGCTTTAAGAATAAAAAATAATGATCCTGCTTTGTGTTTATCCCATGTTGAGTT CTGTGCGGGGCAGAGGGAACACACGGTAAATGCGTTATGGGGAATTATAGGCTACTTGAG GGAGTGACAGTCTGGTGGTAACTCCTGCCTTCCTCCATCAGTGCCACGTTGGCATCCTCT TATGCAGTCAGGCTTCAGGGCTGATGGGTTCAGAACCGAGGGCTTCTGGCTCTGAGTGAG GTCCTGCTGCAAGGTTTCCTAGATGAGCCACTGAGACTCTAATAAGATCCAGTGGAAATA ACCAGGCTCTCGTCGGAATATAAGTCCCAAGGGAAGCTGTGCCAGTCTTGTGGGCGACTG CCTGACTTCTCCTTTCATTTCAGCACCATGAAGCTTCTCACGGGCCTGGTTTTCTGCTCC TTGGTCCTGGGTGTCAGCAGCCGAAGCTTCTTTTCGTTCCTTGGCGAGGCTTTTGATGGT AAGGCTTCAGAAGGTTTGCAGGATTTCTGAAGAGAAACATCACCCTGGACCTGATAAACT GGGGAAAATGATGCTTTCGGAAGGCTGCTTTTGAACCACAGAGTTGCTAGTGTCTGCGTT GCTGAGGCCTGCCAGGAACTAGGGTTTGCTGGGTTGCCTGTCTCGAGTCTTTCAGAGCTG CTGGGAATATCCCCTTTCCCCGTAGTGCAGCTTCTCAGGATGTGTTAAGTGGATGGATCA CATTTCAGAAGCCGCTGCAAGGTGTATCAAAAACACATCTCCTGAGCCGTAAGGGACGGG GCATCCAGTAACAACGCACACGGGGTATTTTTGGGCTTCCTTAAGATTTGAGCCGCTGCC TTAGGTTGTGCTGCCCAATGTGCCTGGGGAGCTGCTAAACAGATTAGAGAGTCGAGGATT GTTGTCAGTTACTCAGAGAAAGAACAATCATCCTTTCCAGGAGCACCTGAGCTGTTTGTT TTGCGTAGAAGATGCAAAATAAGGCCTGCAATGGGTATAAAATGTCCCTCAGCATAAATC GCATAGGAGTATGACTAAGGCTGTTGACTCTTCTGTCTTCTTTCTCCTTCCTCCTTCGAT TTCCTAGTTGGATAATGTACAGGGCTCTTTAGCCTCGCTCTGTCAGGGGCTCCCTTCCTG GTTTGTTCTGTTTCCATTCTTCCTTCTCCAGCCTTCTTGACAAGAGCTGGGAACTAACGT GCCTCAAGCCCCCACAAGGACCACAGCATTTTCTCATTTAGTTTCAGAATGACTCTGTGA CGCAATCTTCCTCTCTTGGAAGGTGAGAAAGCTGATCTTGGAAGGTGAGAAAGCTGAGAC TTAGAGCAGCTGAAGCCAATGCCCAGGGACTTACTGCCAGTCAGCAGGTGGCAGGGCAGA GGTTTGAGCCCGGCTGTGCTTGAGGTCAGGGCTCTTGCCAGGTAGACGCATCACTGACCA CCTCCTAGAGGTTGATGGTTATGAATCTCAGGCACACCTTGGCATCACCTGAAATACCCA TGCCTTCAACTCCCCAGCAGAGTCTGCAGAAACTGGCCTGGGGTGTGGCCTGGGCACTGG GACTTTCAGTTTCTCTCTGGGTGATTAGAAAGTGCAGCCAAGGCTCACGCCTGTAATTCC AGCACTTTGGGAGGCCAAGGTGGATGAATCACTTGAGGTCATGAGTTCCGGAGCAGCCTG GCCAACATGGTGAAACCCCGTCTCTACTAAAAATACTAAAATGTAGCCAGGCGTGGTGGC AGGCACCTGTAATCCCAGCTACTCAGGAGGCTGAAGCACGAGAATCACTTGAACCCGAGA AGCAGAGGTTGCAGTGACTAGAGATCGCACCAGTGTCCTCCAACCTGGGTGACAGAGCGA GACTCCATCTAAAAAAAATGAAAAAGAAAGTGCAGCCAAGGCAGAGCACCACTGCCCTAT TGCTTCCTCAAGCAACCCACAGCATCAGTACAGCCTACTAAGAAAGTATTTAGGGACTTT TATGCTCCTAACAGTCACTGGAACTCACGTCACAATGACGTGTATTCCATTTGCAAGAAT ATATACTTTAGGTCGGGGTGCGGTGGCTCACGCCTGTAATCCCAGCACTTTGGGAGGCCA AGGCAGGGGGATCACGAGGTCAGGAGTTCGAGACCAGCCTGACCAACATGGTGAAATCCC CGTCTCTACTAAAAATACAAAAATTAGCCAGGCGTGATGGCGCATGCCTGTAATCTCAGC TACTCAGGAGGCTGAGGCAGAAGAATCTCTTGAACCTGGGAGGTGGAGGTTGCGATGAGC TGAGATAGCACCACTGCACTCCAGCCTGGGCGACAGAGCAAGACTCTGTCTAAAAAAAAA AAAAAAAAAAAAAAAAAAAAAAAGAATATAAACTTTAGTAGTCAGGGCAGAAGTACTCTG TGTCTGCCACCTTTCTCAGCATCAGTATTCCATGTCACTACCTCATTCATACACACTCCT GGATCTTATCATAGGCAGCTTCATTCTATAGCAGTGGCTCTTCACCAGGGCACTTGAAGA AGCCAACTAGGATAAAGGAATGTGCTTCTCAACCCATGGTATCCAAGGCTGCTATGATCA CAGGCTGAAAGCTTGAAGTCAGTGGAAGATTTGTCCTTCCTCATTCCCCTCTAAGGTGTT GTTGGAGTCTTTATGTTCTCCTGATGTCCCTTCTGCCTTTCCTTTCCTTTCCAGGGGCTC GGGACATGTGGAGAGCCTACTCTGACATGAGAGAAGCCAATTACATCGGCTCAGACAAAT ACTTCCATGCTCGGGGGAACTATGATGCTGCCAAAAGGGGACCTGGGGGTGCCTGGGCTG CAGAAGTGATCACGTAACTGGAGCTCCTGGGACGTTAGGGCTGGGTGAGCAGAGCTTGCC TGCCTTGGACAGTCAGGAGGGAGACGAGCTCCTTGTGGAGAAGTTAGAGGCTGCGGCCCC TCCTCCTCTTGCCCTCTCTCTGCCTCTGTGCTCAGTGTGAGGTCTGAGTGGATGGTAGGA GTGAGTGATTCCTCATCCTCCCTCTCTGGGTGCTGTTCATCCAGCCTAGGGGTGCCCAGC CTGGCTGAATGGGGTGGTGCCCAGTGTTTTCATCCCTCCTTCCTTGGCCTTTCTGGGCTC CTCTCTGAGCCCTCCCTTGGAACAGGGAGAATGGGAGGGTGGGCTATTGCTCACTGGCCT GATTATTAATCTCCTTCTTGCCTGCCTTGATTACAGCGATGCCAGAGAGAATATCCAGAG ATTCTTTGGCCATGGTGCGGAGGACTCGCTGGCTGATCAGGCTGCCAATGAATGGGGCAG GAGTGGCAAAGACCCCAATCACTTCCGACCTGCTGGCCTGCCTGAGAAATACTGAGCTTC CTCTTCACTCTGCTCTCAGGAGATCTGGCTGTGAGGCCCTCAGGGCAGGGATACAAAGCG GGGAGAGGGTACACAATGGGTATCTAATAAATACTTAAGAGGTGGAATTTGTGGAAA OMIM ID 104750