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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for SCN10A (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID6336
Official gene symbolSCN10A
Full namesodium channel, voltage-gated, type X, alpha subunit
Aliases,Nav1.8,PN3,SNS,hPN3,
Gene summaryVoltage-gated sodium channels are integral membrane glycoproteins that are responsible for the initial rising phase of action in most excitable cells. They are composed of a large alpha subunit that may be associated with one or more smaller beta subunits. Sodium channels can be differentiated by their primary structure, kinetics, and relative sensitivity to the neurotoxin tetrodotoxin (TTX). Sodium channels, particularly those with TTX-resistant currents, have been found to accumulate in the region of peripheral nerve injury and may be important in chronic pain. SCN10A encodes a TTX-resistant channel that is restricted to the peripheral sensory nervous system (Rabert et al., 1998 [PubMed 9839820]).[supplied by OMIM]
LocationChromosome: 3   Locus: 3p22-p21
Gene position38835501 - 38738837  Map Viewer
Gene orientationminus
Gene size96665 bp
Gene sequence
OMIM ID604427