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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for CCL8 (Homo sapiens) (Information is obtained from NCBI Gene database)

Entrez gene ID 6355 Official gene symbol CCL8 Full name chemokine (C-C motif) ligand 8 Aliases ,HC14,MCP-2,MCP2,SCYA10,SCYA8, Gene summary This gene is one of several cytokine genes clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The protein encoded by this gene is structurally related to the CXC subfamily of cytokines. Members of this subfamily are characterized by two cysteines separated by a single amino acid. This cytokine displays chemotactic activity for monocytes, lymphocytes, basophils and eosinophils. By recruiting leukocytes to sites of inflammation this cytokine may contribute to tumor-associated leukocyte infiltration and to the antiviral state against HIV infection. [provided by RefSeq] Location Chromosome: 17   Locus: 17q11.2 Gene position 32646066 - 32648421  Map Viewer Gene orientation plus Gene size 2356 bp Gene sequence >CCL8:7383060..7385415:Length=2356 GTGATGGAGAGCACCAGCAAAGCCTTAGGGCCCATCCCTGGCCTCCTGTTACCCACAGAG GGGTAGGCCCTTGGCTCTCTTCCACTATGACGTCAGCTTCCATTCTTCCTTTCTTATAGA CAATTTTCCATTTCAAGGAAATCAGAGCCCTTAATAGTTCAGTGAGGTCACTTTGCTGAG CACAATCCCATACCCTTCAGCCTCTGCTCCACAGAGCCTAAGCAAAAGATAGAAACTCAC AACTTCCTTGTTTTGTTATCTGGAAATTATCCCAGGATCTGGTGCTTACTCAGCATATTC AAGGAAGGTCTTACTTCATTCTTCCTTGATTGTGACCATGCCCAGGCTCTCTGCTCCCTA TAAAAGGCAGGCAGAGCCACCGAGGAGCAGAGAGGTTGAGAACAACCCAGAAACCTTCAC CTCTCATGCTGAAGCTCACACCCTTGCCCTCCAAGATGAAGGTTTCTGCAGCGCTTCTGT GCCTGCTGCTCATGGCAGCCACTTTCAGCCCTCAGGGACTTGCTCAGCCAGGTAAGACCT CTCCCTTTTTAAGGGGAGACCAAAAGAGGAATTAAGAAGAGCCATTATGTCACAGCTCAT TAGGAACAAAACCAGAACTAAAGGCTCAGGTCACTGAGGCTGGTTCCCTTGATCTTTCCT GACCCCAGTTTTGGGAGGAGACAGTGGAGCCGCTACAGCAACAACCCTCCCATTGTTTGG GGAAATAATCCAGAACGAAGAACTGTTTCTCACTGTGGGTGTAAAGGACATTTCAGGCCG TAGTGGAGAGGGAGAAACTATTGCCTGAAGCTTCAAATTTTGGTTATGGTTCAGTGTACC TTCCAGAACAGTGGCTGTGTAAAGAGGATGAGGACCCAGAGGAATCTCAGCGTATGGCAT AGGCTAACTCTAAAGCCCATGAGGATGAAAGACTGGGAAGCAAGGTATTGGAACTTATGT TCCCAGTGTCAGAAGTTTTGGGTTAGTAGACAAGGACTAGCTTGTTACTCAAAATGTTTC CAAACCCAGTCAACAATGACGGGCCGCAGAGTTCAATAGAGGAAAGAGACTCACAGGCAA CATTTTATCTCTGGGATCTGGACTAAGACACTGAACTTGGGATGGTGACTTCTTGGTCTT CTCCTTCCTTCTCTTCTTTTCCTTACAAATGCACACTTACGGTGGGTCCTAAATGTCTCA TTCTTTGCAAAATTTCTTTCAGATTCAGTTTCCATTCCAATCACCTGCTGCTTTAACGTG ATCAATAGGAAAATTCCTATCCAGAGGCTGGAGAGCTACACAAGAATCACCAACATCCAA TGTCCCAAGGAAGCTGTGATGTGAGTGGACAGTGCCTGGCACCCCCATTCAAAAGTTCTG ATGGACAACATAGAGAAGTCAAGATTCATGTCCATATGAGTCGGATGCATATAACTTCTA TCCAAAGGGCCCCTCTACCCCATAGAGAAACTCAGTCCATGAGAAGGAGTCCATAACTGC TCTAGGATTCCCTTCTAGGGGCTTGGTGAAACTAACCCAATATCTGTAGCCAGGACCCTG GAGGGTTTCACCTGGACAGCAAGAGCAGAGCTTCCTTCTGGAGCTTCTTCCTCCCACTCT TCCCCTCCCTCCTCTCCCGGGTCCGGGTCCTTCACCTAAGGACCAAGGGCTGATCAGTTC TAGGGACCAATGGCCCACAGTCCTGTGCAGGATCTTCAAAGTCTTCCATCTAATTGTGCC CTCTCTCCCCCACAGCTTCAAGACCAAACGGGGCAAGGAGGTCTGTGCTGACCCCAAGGA GAGATGGGTCAGGGATTCCATGAAGCATCTGGACCAAATATTTCAAAATCTGAAGCCATG AGCCTTCATACATGGACTGAGAGTCAGAGCTTGAAGAAAAGCTTATTTATTTTCCCCAAC CTCCCCCAGGTGCAGTGTGACATTATTTTATTATAACATCCACAAAGAGATTATTTTTAA ATAATTTAAAGCATAATATTTCTTAAAAAGTATTTAATTATATTTAAGTTGTTGATGTTT TAACTCTATCTGTCATACATCCTAGTGAATGTAAAATGCAAAATCCTGGTGATGTGTTTT TTGTTTTTGTTTTCCTGTGAGCTCAACTAAGTTCACGGCAAAATGTCATTGTTCTCCCTC CTACCTGTCTGTAGTGTTGTGGGGTCCTCCCATGGATCATCAAGGTGAAACACTTTGGTA TTCTTTGGCAATCAGTGCTCCTGTAAGTCAAATGTGTGCTTTGTACTGCTGTTGTTGAAA TTGATGTTACTGTATATAACTATGGAATTTTGAAAAAAAATTTCAAAAAGAAAAAAATAT ATATAATTTAAAACTA OMIM ID 602283