Entrez gene ID | | 6368 |
Official gene symbol | | CCL23 |
Full name | | chemokine (C-C motif) ligand 23 |
Aliases | | ,CK-BETA-8,CKb8,Ckb-8,Ckb-8-1,MIP-3,MIP3,MPIF-1,SCYA23, |
Gene summary | | This gene is one of several cytokine genes clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity on resting T lymphocytes and monocytes, lower activity on neutrophils and no activity on activated T lymphocytes. The protein is also a strong suppressor of colony formation by a multipotential hematopoietic progenitor cell line. In addition, the product of this gene is a potent agonist at CC chemokine receptor 1. Two alternatively spliced variants encoding different active isoforms have been identified. [provided by RefSeq] |
Location | | Chromosome: 17 Locus: 17q12 |
Gene position | | 34345005 - 34340097 Map Viewer |
Gene orientation | | minus |
Gene size | | 4909 bp |
Gene sequence |
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OMIM ID | | 602494 |
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