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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for BID (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID637
Official gene symbolBID
Full nameBH3 interacting domain death agonist
Aliases,FP497,MGC15319,MGC42355,
Gene summaryThis gene encodes a death agonist that heterodimerizes with either agonist BAX or antagonist BCL2. The encoded protein is a member of the BCL-2 family of cell death regulators. It is a mediator of mitochondrial damage induced by caspase-8 (CASP8); CASP8 cleaves this encoded protein, and the COOH-terminal part translocates to mitochondria where it triggers cytochrome c release. Multiple alternatively spliced transcript variants have been found, but the full-length nature of some variants has not been defined. [provided by RefSeq]
LocationChromosome: 22   Locus: 22q11.1
Gene position18257258 - 18216906  Map Viewer
Gene orientationminus
Gene size40353 bp
Gene sequence
OMIM ID601997