Entrez gene ID | | 637 |
Official gene symbol | | BID |
Full name | | BH3 interacting domain death agonist |
Aliases | | ,FP497,MGC15319,MGC42355, |
Gene summary | | This gene encodes a death agonist that heterodimerizes with either agonist BAX or antagonist BCL2. The encoded protein is a member of the BCL-2 family of cell death regulators. It is a mediator of mitochondrial damage induced by caspase-8 (CASP8); CASP8 cleaves this encoded protein, and the COOH-terminal part translocates to mitochondria where it triggers cytochrome c release. Multiple alternatively spliced transcript variants have been found, but the full-length nature of some variants has not been defined. [provided by RefSeq] |
Location | | Chromosome: 22 Locus: 22q11.1 |
Gene position | | 18257258 - 18216906 Map Viewer |
Gene orientation | | minus |
Gene size | | 40353 bp |
Gene sequence |
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OMIM ID | | 601997 |