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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for CXCL11 (Homo sapiens) (Information is obtained from NCBI Gene database)

Entrez gene ID 6373 Official gene symbol CXCL11 Full name chemokine (C-X-C motif) ligand 11 Aliases ,H174,I-TAC,IP-9,IP9,MGC102770,SCYB11,SCYB9B,b-R1, Gene summary Chemokines are a group of small (approximately 8 to 14 kD), mostly basic, structurally related molecules that regulate cell trafficking of various types of leukocytes through interactions with a subset of 7-transmembrane, G protein-coupled receptors. Chemokines also play fundamental roles in the development, homeostasis, and function of the immune system, and they have effects on cells of the central nervous system as well as on endothelial cells involved in angiogenesis or angiostasis. Chemokines are divided into 2 major subfamilies, CXC and CC. This gene is a CXC member of the chemokine superfamily. Its encoded protein induces a chemotactic response in activated T-cells and is the dominant ligand for CXC receptor-3. The gene encoding this protein contains 4 exons and at least three polyadenylation signals which might reflect cell-specific regulation of expression. IFN-gamma is a potent inducer of transcription of this gene. [provided by RefSeq] Location Chromosome: 4   Locus: 4q21.2 Gene position 76957233 - 76954835  Map Viewer Gene orientation minus Gene size 2399 bp Gene sequence >CXCL11:complement(1502556..1504954):Length=2399 TTCCTTTCATGTTCAGCATTTCTACTCCTTCCAAGAAGAGCAGCAAAGCTGAAGTAGCAG CAGCAGCACCAGCAGCAACAGCAAAAAACAAACATGAGTGTGAAGGGCATGGCTATAGCC TTGGCTGTGATATTGTGTGCTACAGTTGTTCAAGGTATGCAGTAATTTTTATTTCTCAAC CTATAAGTTCCTTTTCTAATGTTTCAAATGTCTTTTCTTCCACTTTTATCCTAAAAGACA TGATAAAGTTTTATTTAATCTCACAGATTAGAAGTTACTACAGCTTTAGCACAGAAATGG TGGACATGTTTAAGATACTAGAGATGATTATTGAAACTAGAAATTATGAACTTCATGGAA TTTTTGATTTGGCTAGAATATCTGGCAAAAGCCTTTAGCAACAGTTTTAAATGTCTGTTA AGAAGATTTTATATAGCGATCATGTTAACAAGCTTCCTGGGAAAATATTTGAGGATAAAA TCAAGGGGGCAAAACAAGCTTCACCTCCAATAAACTTCCTTCATGCTTCCCATTTGTTAG CGATTTGCTTACTAATTTAATGAGAAAATAATCAACATCTTACTTAACTTTTCCCAGTAA CAGTTGTGTTAAGTGCTATTTGACAAATTACTATCTTTACCCTTAATGAAAATTCTGCTC ACGTTCACCACCAGCTATAAACCACAGCCATCTGTTGCAATCAGATGCATTACTAACTAA TGCTATGATCTATTCTAGGCTTCCCCATGTTCAAAAGAGGACGCTGTCTTTGCATAGGCC CTGGGGTAAAAGCAGTGAAAGTGGCAGATATTGAGAAAGCCTCCATAATGTACCCAAGTA ACAACTGTGACAAAATAGAAGTGATGTAAGTAATGAACTTGCTGAAGATGACAATGGTGC AGGCTTTTTTGTTTATGTATTTGCATCTAAACTTTAAGACTCTTGTATGTTCTTTTAACA GTATTACCCTGAAAGAAAATAAAGGACAACGATGCCTAAATCCCAAATCGAAGCAAGCAA GGCTTATAATCAAAGTAAGTTACCAAATTACTCCCATGTTATAATCTGTTTTATCCAAGA CAGATCTTTTGAAAAAGAAAATAATGTGGACAACTACAGAAAGATTCTGCTATGATCCTG TGTGAAATATTCTGTTAAGGGGTCCTTGGTTGTAACAGCTTCCCCTTCTTACTACATGTT TTTAGATGTCCTGGGGGAAACAAGAACAGCCCAAGTAAATAAAACTCTTGTTTTCTTATT CCAGAAAGTTGAAAGAAAGAATTTTTAAAAATATCAAAACATATGAAGTCCTGGAAAAGA GCATCTGAAAAACCTAGAACAAGTTTAACTGTGACTACTGAAATGACAAGAATTCTACAG TAGGAAACTGAGACTTTTCTATGGTTTTGTGACTTTCAACTTTTGTACAGTTATGTGAAG GATGAAAGGTGGGTGAAAGGACCAAAAACAGAAATACAGTCTTCCTGAATGAATGACAAT CAGAATTCCACTGCCCAAAGGAGTCCAACAATTAAATGGATTTCTAGGAAAAGCTACCTT AAGAAAGGCTGGTTACCATCGGAGTTTACAAAGTGCTTTCACGTTCTTACTTGTTGCATT ATACATTCATGCATTTCTAGGCTAGAGAACCTTCTAGATTTGATGCTTACAACTATTCTG TTGTGACTATGAGAACATTTCTGTCTCTAGAAGTCATCTGTCTGTATTGATCTTTATGCT ATATTACTATCTGTGGTTACGGTGGAGACATTGACATTATTACTGGAGTCAAGCCCTTAT AAGTCAAAAGCATCTATGTGTCGTAAAACATTCCTCAAACATTTTTTCATGCAAATACAC ACTTCTTTCCCCAAACATCATGTAGCACATCAATATGTAGGGAGACATTCTTATGCATCA TTTGGTTTGTTTTATAACCAATTCATTAAATGTAATTCATAAAATGTACTATGAAAAAAA TTATACGCTATGGGATACTGGCAAAAGTGCACATATTTCATAACCAAATTAGTAGCACCA GTCTTAATTTGATGTTTTTCAACTTTTATTCATTGAGATGTTTTGAAGCAATTAGGATAT GTGTGTTTACTGTACTTTTTGTTTTGATCCGTTTGTATAAATGATAGCAATATCTTGGAC ACATCTGAAATACAAAATGTTTTTGTCTACCAAAGAAAAATGTTGAAAAATAAGCAAATG TATACCTAGCAATCACTTTTACTTTTTGTAATTCTGTCTCTTAGAAAAATACATAATCTA ATCAATTTCTTTGTTCATGCCTATATACTGTAAAATTTAGGTATACTCAAGACTAGTTTA AAGAATCAAAGTCATTTTTTTCTCTAATAAACTACCACAACCTTTCTTTTTTAAAAAAA OMIM ID 604852