Entrez gene ID | | 6382 |
Official gene symbol | | SDC1 |
Full name | | syndecan 1 |
Aliases | | ,CD138,SDC,SYND1,syndecan, |
Gene summary | | The protein encoded by this gene is a transmembrane (type I) heparan sulfate proteoglycan and is a member of the syndecan proteoglycan family. The syndecans mediate cell binding, cell signaling, and cytoskeletal organization and syndecan receptors are required for internalization of the HIV-1 tat protein. The syndecan-1 protein functions as an integral membrane protein and participates in cell proliferation, cell migration and cell-matrix interactions via its receptor for extracellular matrix proteins. Altered syndecan-1 expression has been detected in several different tumor types. While several transcript variants may exist for this gene, the full-length natures of only two have been described to date. These two represent the major variants of this gene and encode the same protein. [provided by RefSeq] |
Location | | Chromosome: 2 Locus: 2p24.1 |
Gene position | | 20425194 - 20400558 Map Viewer |
Gene orientation | | minus |
Gene size | | 24637 bp |
Gene sequence |
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OMIM ID | | 186355 |
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