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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for SDC1 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID6382
Official gene symbolSDC1
Full namesyndecan 1
Aliases,CD138,SDC,SYND1,syndecan,
Gene summaryThe protein encoded by this gene is a transmembrane (type I) heparan sulfate proteoglycan and is a member of the syndecan proteoglycan family. The syndecans mediate cell binding, cell signaling, and cytoskeletal organization and syndecan receptors are required for internalization of the HIV-1 tat protein. The syndecan-1 protein functions as an integral membrane protein and participates in cell proliferation, cell migration and cell-matrix interactions via its receptor for extracellular matrix proteins. Altered syndecan-1 expression has been detected in several different tumor types. While several transcript variants may exist for this gene, the full-length natures of only two have been described to date. These two represent the major variants of this gene and encode the same protein. [provided by RefSeq]
LocationChromosome: 2   Locus: 2p24.1
Gene position20425194 - 20400558  Map Viewer
Gene orientationminus
Gene size24637 bp
Gene sequence
OMIM ID186355