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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for MRPS14 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID63931
Official gene symbolMRPS14
Full namemitochondrial ribosomal protein S14
Aliases,DJ262D12.2,HSMRPS14,MRP-S14,
Gene summaryMammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that belongs to the ribosomal protein S14P family. Alternative splicing results in multiple transcript variants. [provided by RefSeq]
LocationChromosome: 1   Locus: 1q23-q25
Gene position174992561 - 174983128  Map Viewer
Gene orientationminus
Gene size9434 bp
Gene sequence
OMIM ID611978