Entrez gene ID | | 6402 |
Official gene symbol | | SELL |
Full name | | selectin L |
Aliases | | ,CD62L,LAM1,LECAM1,LEU8,LNHR,LSEL,LYAM1,PLNHR,TQ1, |
Gene summary | | This gene encodes a cell surface adhesion molecule that belongs to a family of adhesion/homing receptors. The encoded protein contains a C-type lectin-like domain, a calcium-binding epidermal growth factor-like domain, and two short complement-like repeats. The gene product is required for binding and subsequent rolling of leucocytes on endothelial cells, facilitating their migration into secondary lymphoid organs and inflammation sites. Single-nucleotide polymorphisms in this gene have been associated with various diseases including immunoglobulin A nephropathy. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq] |
Location | | Chromosome: 1 Locus: 1q23-q25 |
Gene position | | 169680843 - 169659806 Map Viewer |
Gene orientation | | minus |
Gene size | | 21038 bp |
Gene sequence |
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OMIM ID | | 153240 |
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