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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for EDDM3B (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID64184
Official gene symbolEDDM3B
Full nameepididymal protein 3B
Aliases,EP3B,FAM12B,HE3-BETA,HE3B,
Gene summaryTesticular sperm are morphologically differentiated but are not progressively motile nor able to fertilize an egg. Post-testicular maturation requires exposure of spermatozoa to the microenvironment of the epididymal lumen. Spermatozoa undergo extensive changes in the epididymis, including enzymatic modifications, loss of pre-existing components and addition of new glycoproteins from epididymal secretions. These modifying proteins and enzymes are synthesized by epithelial cells lining the epididymal duct and secreted apically into the lumen, where they come into contact with, and may be absorbed onto, the sperm membranes. The proteins encoded by the genes in this cluster are synthesized and secreted by epididymal epithelial cells. [provided by RefSeq]
LocationChromosome: 14   Locus: 14q11.2
Gene position21236586 - 21239107  Map Viewer
Gene orientationplus
Gene size2522 bp
Gene sequence
OMIM ID611582