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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for ABCG5 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID64240
Official gene symbolABCG5
Full nameATP-binding cassette, sub-family G (WHITE), member 5
Aliases,STSL,
Gene summaryThe protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. The protein encoded by this gene functions as a half-transporter to limit intestinal absorption and promote biliary excretion of sterols. It is expressed in a tissue-specific manner in the liver, colon, and intestine. This gene is tandemly arrayed on chromosome 2, in a head-to-head orientation with family member ABCG8. Mutations in this gene may contribute to sterol accumulation and atheroschlerosis, and have been observed in patients with sitosterolemia. [provided by RefSeq]
LocationChromosome: 2   Locus: 2p21
Gene position44065958 - 44039611  Map Viewer
Gene orientationminus
Gene size26348 bp
Gene sequence
OMIM ID605459