| Entrez gene ID | | 6426 |
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| Official gene symbol | | SRSF1 |
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| Full name | | splicing factor, arginine/serine-rich 1 |
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| Aliases | | ,ASF,SF2,SF2p33,SFRS1,SRp30a, |
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| Gene summary | | This gene encodes a member of the arginine/serine-rich splicing factor protein family, and functions in both constitutive and alternative pre-mRNA splicing. The protein binds to pre-mRNA transcripts and components of the spliceosome, and can either activate or repress splicing depending on the location of the pre-mRNA binding site. The protein's ability to activate splicing is regulated by phosphorylation and interactions with other splicing factor associated proteins. Multiple transcript variants encoding different isoforms have been found for this gene. In addition, a pseudogene of this gene has been found on chromosome 13. [provided by RefSeq] |
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| Location | | Chromosome: 17 Locus: 17q21.3-q22 |
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| Gene position | | 56084707 - 56078280 Map Viewer |
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| Gene orientation | | minus |
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| Gene size | | 6428 bp |
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| Gene sequence |
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| OMIM ID | | 600812 |
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