Database of mammalian genes
Home

Home Search Browse Statistics User guide FAQs Links Questions Contribute Download


Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for SRSF2 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID6427
Official gene symbolSRSF2
Full namesplicing factor, arginine/serine-rich 2
Aliases,PR264,SC-35,SC35,SFRS2,SFRS2A,SRp30b,
Gene summaryThe protein encoded by this gene is a member of the serine/arginine (SR)-rich family of pre-mRNA splicing factors, which constitute part of the spliceosome. Each of these factors contains an RNA recognition motif (RRM) for binding RNA and an RS domain for binding other proteins. The RS domain is rich in serine and arginine residues and facilitates interaction between different SR splicing factors. In addition to being critical for mRNA splicing, the SR proteins have also been shown to be involved in mRNA export from the nucleus and in translation. Two transcript variants encoding the same protein and one non-coding transcript variant have been found for this gene. In addition, a pseudogene of this gene has been found on chromosome 11. [provided by RefSeq]
LocationChromosome: 17   Locus: 17q25.1
Gene position74733412 - 74730197  Map Viewer
Gene orientationminus
Gene size3216 bp
Gene sequence
OMIM ID600813