Entrez gene ID | | 643 |
Official gene symbol | | CXCR5 |
Full name | | chemokine (C-X-C motif) receptor 5 |
Aliases | | ,BLR1,CD185,MDR15,MGC117347, |
Gene summary | | This gene was identified as a gene specifically expressed in Burkitt's lymphoma and lymphatic tissues. The protein encoded by this gene is predicted to be a seven transmembrane G protein- coupled receptor and belongs to the CXC chemokine receptor family. BLC, a B-lymphocyte chemoattractant, was identified to be a specific ligand for this receptor. Studies of this gene and its mouse conterpart strongly suggest the essential function of this gene in B cell migration and localization within specific anatomic compartments, such as follicles in lymph nodes as well as in spleen. Two alternatively spliced variants of this gene exist. [provided by RefSeq] |
Location | | Chromosome: 11 Locus: 11q23.3 |
Gene position | | 118754541 - 118766971 Map Viewer |
Gene orientation | | plus |
Gene size | | 12431 bp |
Gene sequence |
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OMIM ID | | 601613 |