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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for LMBR1 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID64327
Official gene symbolLMBR1
Full namelimb region 1 homolog (mouse)
Aliases,ACHP,C7orf2,DIF14,FLJ11665,PPD2,TPT,
Gene summaryThis gene encodes a member of the LMBR1-like membrane protein family. Another member of this protein family has been shown to be a lipocalin transmembrane receptor. A highly conserved, cis-acting regulatory module for the sonic hedgehog gene is located within an intron of this gene. Consequently, disruption of this genic region can alter sonic hedgehog expression and affect limb patterning, but it is not known if this gene functions directly in limb development. Mutations and chromosomal deletions and rearrangements in this genic region are associated with acheiropody and preaxial polydactyly, which likely result from altered sonic hedgehog expression. [provided by RefSeq]
LocationChromosome: 7   Locus: 7q36
Gene position156685902 - 156473570  Map Viewer
Gene orientationminus
Gene size212333 bp
Gene sequence
OMIM ID605522