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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for NFKBIZ (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID64332
Official gene symbolNFKBIZ
Full namenuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta
Aliases,FLJ30225,FLJ34463,IKBZ,INAP,MAIL,
Gene summaryThis gene is a member of the ankyrin-repeat family and is induced by lipopolysaccharide (LPS). The C-terminal portion of the encoded product which contains the ankyrin repeats, shares high sequence similarity with the I kappa B family of proteins. The latter are known to play a role in inflammatory responses to LPS by their interaction with NF-B proteins through ankyrin-repeat domains. Studies in mouse indicate that this gene product is one of the nuclear I kappa B proteins and an activator of IL-6 production. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
LocationChromosome: 3   Locus: 3p12-q12
Gene position101546834 - 101579869  Map Viewer
Gene orientationplus
Gene size33036 bp
Gene sequence
OMIM ID608004