Entrez gene ID | | 64344 |
Official gene symbol | | HIF3A |
Full name | | hypoxia inducible factor 3, alpha subunit |
Aliases | | ,HIF-3A,HIF-3A2,HIF-3A4,IPAS,MOP7,PASD7,bHLHe17, |
Gene summary | | The protein encoded by this gene is the alpha-3 subunit of one of several alpha/beta-subunit heterodimeric transcription factors that regulate many adaptive responses to low oxygen tension (hypoxia). The alpha-3 subunit lacks the transactivation domain found in factors containing either the alpha-1 or alpha-2 subunits. It is thought that factors containing the alpha-3 subunit are negative regulators of hypoxia-inducible gene expression. At least three transcript variants encoding three different isoforms have been found for this gene. [provided by RefSeq] |
Location | | Chromosome: 19 Locus: 19q13.32 |
Gene position | | 46800305 - 46846690 Map Viewer |
Gene orientation | | plus |
Gene size | | 46386 bp |
Gene sequence |
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OMIM ID | | 609976 |