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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for GREM2 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID64388
Official gene symbolGREM2
Full namegremlin 2, cysteine knot superfamily, homolog (Xenopus laevis)
Aliases,CKTSF1B2,DAND3,PRDC,
Gene summaryThis gene encodes a member of the BMP (bone morphogenic protein) antagonist family. Like BMPs, BMP antagonists contain cystine knots and typically form homo- and heterodimers. The CAN (cerberus and dan) subfamily of BMP antagonists, to which this gene belongs, is characterized by a C-terminal cystine knot with an eight-membered ring. The antagonistic effect of the secreted glycosylated protein encoded by this gene is likely due to its direct binding to BMP proteins. As an antagonist of BMP, this gene may play a role in regulating organogenesis, body patterning, and tissue differentiation. [provided by RefSeq]
LocationChromosome: 1   Locus: 1q43
Gene position240775462 - 240652873  Map Viewer
Gene orientationminus
Gene size122590 bp
Gene sequence
OMIM ID608832