Entrez gene ID | | 6446 |
Official gene symbol | | SGK1 |
Full name | | serum/glucocorticoid regulated kinase 1 |
Aliases | | ,SGK, |
Gene summary | | This gene encodes a serine/threonine protein kinase that plays an important role in cellular stress response. This kinase activates certain potassium, sodium, and chloride channels, suggesting an involvement in the regulation of processes such as cell survival, neuronal excitability, and renal sodium excretion. High levels of expression of this gene may contribute to conditions such as hypertension and diabetic nephropathy. Several alternatively spliced transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq] |
Location | | Chromosome: 6 Locus: 6q23 |
Gene position | | 134639196 - 134490384 Map Viewer |
Gene orientation | | minus |
Gene size | | 148813 bp |
Gene sequence |
| |
OMIM ID | | 602958 |
|