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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for CLEC7A (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID64581
Official gene symbolCLEC7A
Full nameC-type lectin domain family 7, member A
Aliases,BGR,CANDF4,CLECSF12,DECTIN1,
Gene summaryThis gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. The encoded glycoprotein is a small type II membrane receptor with an extracellular C-type lectin-like domain fold and a cytoplasmic domain with an immunoreceptor tyrosine-based activation motif. It functions as a pattern-recognition receptor that recognizes a variety of beta-1,3-linked and beta-1,6-linked glucans from fungi and plants, and in this way plays a role in innate immune response. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. This gene is closely linked to other CTL/CTLD superfamily members on chromosome 12p13 in the natural killer gene complex region. [provided by RefSeq]
LocationChromosome: 12   Locus: 12p13.2
Gene position10282868 - 10269376  Map Viewer
Gene orientationminus
Gene size13493 bp
Gene sequence
OMIM ID606264