Entrez gene ID | | 6489 |
Official gene symbol | | ST8SIA1 |
Full name | | ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1 |
Aliases | | ,GD3S,SIAT8,SIAT8A,ST8SiaI, |
Gene summary | | Gangliosides are membrane-bound glycosphingolipids containing sialic acid. Ganglioside GD3 is known to be important for cell adhesion and growth of cultured malignant cells. The protein encoded by this gene is a type II membrane protein that catalyzes the transfer of sialic acid from CMP-sialic acid to GM3 to produce gangliosides GD3 and GT3. The encoded protein may be found in the Golgi apparatus and is a member of glycosyltransferase family 29. [provided by RefSeq] |
Location | | Chromosome: 12 Locus: 12p12.1-p11.2 |
Gene position | | 22487648 - 22346325 Map Viewer |
Gene orientation | | minus |
Gene size | | 141324 bp |
Gene sequence |
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OMIM ID | | 601123 |