Database of mammalian genes
Home

Home Search Browse Statistics User guide FAQs Links Questions Contribute Download


Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for SIM2 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID6493
Official gene symbolSIM2
Full namesingle-minded homolog 2 (Drosophila)
Aliases,MGC119447,SIM,bHLHe15,
Gene summarySIM1 and SIM2 genes are Drosophila single-minded (sim) gene homologs. The Drosophila sim gene encodes a transcription factor that is a master regulator of fruit fly neurogenesis. SIM2 maps within the so-called Down syndrome chromosomal region. Based on the mapping position, its potential function as transcriptional repressor and similarity to Drosophila sim, it is proposed that SIM2 may contribute to some specific Down syndrome phenotypes [provided by RefSeq]
LocationChromosome: 21   Locus: 21q22.2|21q22.13
Gene position38071991 - 38122510  Map Viewer
Gene orientationplus
Gene size50520 bp
Gene sequence
OMIM ID600892