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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for MRPS11 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID64963
Official gene symbolMRPS11
Full namemitochondrial ribosomal protein S11
Aliases,FLJ22512,FLJ23406,HCC-2,
Gene summaryMammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that contains a high level of sequence similarity with ribosomal protein S11P family members. A pseudogene corresponding to this gene is found on chromosome 20. Sequence analysis identified two transcript variants that encode different protein isoforms. [provided by RefSeq]
LocationChromosome: 15   Locus: 15q25
Gene position89010684 - 89021495  Map Viewer
Gene orientationplus
Gene size10812 bp
Gene sequence
OMIM ID611977