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Gene information for MRPL1 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID65008
Official gene symbolMRPL1
Full namemitochondrial ribosomal protein L1
Aliases,BM022,FLJ96680,L1MT,MRP-L1,
Gene summaryMammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein that belongs to the L1 ribosomal protein family. [provided by RefSeq]
LocationChromosome: 4   Locus: 4q21.1
Gene position78783805 - 78873944  Map Viewer
Gene orientationplus
Gene size90140 bp
Gene sequence
OMIM ID611821