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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for SLC6A4 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID6532
Official gene symbolSLC6A4
Full namesolute carrier family 6 (neurotransmitter transporter, serotonin), member 4
Aliases,5-HTT,5-HTTLPR,5HTT,HTT,OCD1,SERT,hSERT,
Gene summaryThis gene encodes an integral membrane protein that transports the neurotransmitter serotonin from synaptic spaces into presynaptic neurons. The encoded protein terminates the action of serotonin and recycles it in a sodium-dependent manner. This protein is a target of psychomotor stimulants, such as amphetamines and cocaine, and is a member of the sodium:neurotransmitter symporter family. A repeat length polymorphism in the promoter of this gene has been shown to affect the rate of serotonin uptake and may play a role in sudden infant death syndrome, aggressive behavior in Alzheimer disease patients, and depression-susceptibility in people experiencing emotional trauma. [provided by RefSeq]
LocationChromosome: 17   Locus: 17q11.1-q12
Gene position28562954 - 28523376  Map Viewer
Gene orientationminus
Gene size39579 bp
Gene sequence
OMIM ID182138