Entrez gene ID | | 6532 |
Official gene symbol | | SLC6A4 |
Full name | | solute carrier family 6 (neurotransmitter transporter, serotonin), member 4 |
Aliases | | ,5-HTT,5-HTTLPR,5HTT,HTT,OCD1,SERT,hSERT, |
Gene summary | | This gene encodes an integral membrane protein that transports the neurotransmitter serotonin from synaptic spaces into presynaptic neurons. The encoded protein terminates the action of serotonin and recycles it in a sodium-dependent manner. This protein is a target of psychomotor stimulants, such as amphetamines and cocaine, and is a member of the sodium:neurotransmitter symporter family. A repeat length polymorphism in the promoter of this gene has been shown to affect the rate of serotonin uptake and may play a role in sudden infant death syndrome, aggressive behavior in Alzheimer disease patients, and depression-susceptibility in people experiencing emotional trauma. [provided by RefSeq] |
Location | | Chromosome: 17 Locus: 17q11.1-q12 |
Gene position | | 28562954 - 28523376 Map Viewer |
Gene orientation | | minus |
Gene size | | 39579 bp |
Gene sequence |
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OMIM ID | | 182138 |
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