Entrez gene ID | | 656 |
Official gene symbol | | BMP8B |
Full name | | bone morphogenetic protein 8b |
Aliases | | ,BMP8,MGC131757,OP2, |
Gene summary | | The bone morphogenetic proteins (BMPs) are a family of secreted signaling molecules that can induce ectopic bone growth. Many BMPs are part of the transforming growth factor-beta (TGFB) superfamily. BMPs were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. Based on its expression early in embryogenesis, the BMP encoded by this gene has a proposed role in early development. In addition, the fact that this BMP is closely related to BMP5 and BMP7 has led to speculation of possible bone inductive activity. [provided by RefSeq] |
Location | | Chromosome: 1 Locus: 1p35-p32 |
Gene position | | 40254533 - 40223903 Map Viewer |
Gene orientation | | minus |
Gene size | | 30631 bp |
Gene sequence |
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OMIM ID | | 602284 |
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