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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for SLC19A1 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID6573
Official gene symbolSLC19A1
Full namesolute carrier family 19 (folate transporter), member 1
Aliases,CHMD,FOLT,IFC1,REFC,RFC1,
Gene summaryTransport of folate compounds into mammalian cells can occur via receptor-mediated (see MIM 136430) or carrier-mediated mechanisms. A functional coordination between these 2 mechanisms has been proposed to be the method of folate uptake in certain cell types. Methotrexate (MTX) is an antifolate chemotherapeutic agent that is actively transported by the carrier-mediated uptake system. RFC1 plays a role in maintaining intracellular concentrations of folate.[supplied by OMIM]
LocationChromosome: 21   Locus: 21q22.3
Gene position46962351 - 46934629  Map Viewer
Gene orientationminus
Gene size27723 bp
Gene sequence
OMIM ID600424