| Entrez gene ID | | 6590 |
|
| Official gene symbol | | SLPI |
|
| Full name | | secretory leukocyte peptidase inhibitor |
|
| Aliases | | ,ALK1,ALP,BLPI,HUSI,HUSI-I,MPI,WAP4,WFDC4, |
|
| Gene summary | | This gene encodes a secreted inhibitor which protects epithelial tissues from serine proteases. It is found in various secretions including seminal plasma, cervical mucus, and bronchial secretions, and has affinity for trypsin, leukocyte elastase, and cathepsin G. Its inhibitory effect contributes to the immune response by protecting epithelial surfaces from attack by endogenous proteolytic enzymes; the protein is also thought to have broad-spectrum anti-biotic activity. [provided by RefSeq] |
|
| Location | | Chromosome: 20 Locus: 20q12 |
|
| Gene position | | 43883206 - 43880879 Map Viewer |
|
| Gene orientation | | minus |
|
| Gene size | | 2328 bp |
|
| Gene sequence |
| |
|
| OMIM ID | | 107285 |
|
|
|
