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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for SMARCE1 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID6605
Official gene symbolSMARCE1
Full nameSWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1
Aliases,BAF57,
Gene summaryThe protein encoded by this gene is part of the large ATP-dependent chromatin remodeling complex SWI/SNF, which is required for transcriptional activation of genes normally repressed by chromatin. The encoded protein, either alone or when in the SWI/SNF complex, can bind to 4-way junction DNA, which is thought to mimic the topology of DNA as it enters or exits the nucleosome. The protein contains a DNA-binding HMG domain, but disruption of this domain does not abolish the DNA-binding or nucleosome-displacement activities of the SWI/SNF complex. Unlike most of the SWI/SNF complex proteins, this protein has no yeast counterpart. [provided by RefSeq]
LocationChromosome: 17   Locus: 17q21.2
Gene position38804103 - 38783972  Map Viewer
Gene orientationminus
Gene size20132 bp
Gene sequence
OMIM ID603111