Entrez gene ID | | 6614 |
Official gene symbol | | SIGLEC1 |
Full name | | sialic acid binding Ig-like lectin 1, sialoadhesin |
Aliases | | ,CD169,DKFZp667F058,FLJ00051,FLJ00055,FLJ00073,FLJ00411,FLJ32150,SIGLEC-1,SN,dJ1009E24.1, |
Gene summary | | This gene encodes a member of the immunoglobulin superfamily. The encoded protein is a lectin-like adhesion molecule that binds glycoconjugate ligands on cell surfaces in a sialic acid-dependent manner. It is a type I transmembrane protein expressed only by a subpopulation of macrophages and is involved in mediating cell-cell interactions. Alternative splicing produces a transcript variant encoding an isoform that is soluble rather than membrane-bound; however, the full-length nature of this variant has not been determined. [provided by RefSeq] |
Location | | Chromosome: 20 Locus: 20p13 |
Gene position | | 3687775 - 3667617 Map Viewer |
Gene orientation | | minus |
Gene size | | 20159 bp |
Gene sequence |
| |
OMIM ID | | 600751 |
|