Entrez gene ID | | 6620 |
Official gene symbol | | SNCB |
Full name | | synuclein, beta |
Aliases | | ,-, |
Gene summary | | The protein encoded by this gene is highly homologous to alpha-synuclein. These proteins are abundantly expressed in the brain and putatively inhibit phospholipase D2 selectively. The encoded protein, which may play a role in neuronal plasticity, is abundant in neurofibrillary lesions of patients with Alzheimer disease. This protein has been shown to be highly expressed in the substantia nigra of the brain, a region of neuronal degeneration in patients with Parkinson disease; however, no direct relation to Parkinson disease has been established. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq] |
Location | | Chromosome: 5 Locus: 5q35 |
Gene position | | 176057557 - 176047210 Map Viewer |
Gene orientation | | minus |
Gene size | | 10348 bp |
Gene sequence |
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