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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for SOD3 (Homo sapiens) (Information is obtained from NCBI Gene database)

Entrez gene ID 6649 Official gene symbol SOD3 Full name superoxide dismutase 3, extracellular Aliases ,EC-SOD,MGC20077, Gene summary This gene encodes a member of the superoxide dismutase (SOD) protein family. SODs are antioxidant enzymes that catalyze the dismutation of two superoxide radicals into hydrogen peroxide and oxygen. The product of this gene is thought to protect the brain, lungs, and other tissues from oxidative stress. The protein is secreted into the extracellular space and forms a glycosylated homotetramer that is anchored to the extracellular matrix (ECM) and cell surfaces through an interaction with heparan sulfate proteoglycan and collagen. A fraction of the protein is cleaved near the C-terminus before secretion to generate circulating tetramers that do not interact with the ECM. [provided by RefSeq] Location Chromosome: 4   Locus: 4p15.3-p15.1 Gene position 24797085 - 24802467  Map Viewer Gene orientation plus Gene size 5383 bp Gene sequence >SOD3:15978882..15984264:Length=5383 GGGGAGGTCTGGCCTGCTTTTCCTCCCTGAACTGGCCCAATGACTGGCTCCCTCACGCTG ACCACTCCTCTGGGCTGGCCTCCTGCACTCGCGCTAACAGCCCAGGCTCCAGGGACAGCC TGCGTTCCTGGGCTGGCTGGGTGCAGCTCTCTTTTCAGGAGAGAAAGCTCTCTTGGAGGA GCTGGAAAGGTGGGTGCTAAGTTGAGGTTCATTTTGTTCTTCTCGGAGTGTGCTTATTGA GTCTGAAGCTGGGTTGGGGCAACGGGCCTCTTCTTGGGAACAAATTGGATCATCTTCTTG GGAAGGAAATGTACTTTCCCTGGCTGCTCTGAGGGGTTAGTGGGGAGGTGGAGTGAGCGG GGAGGAAGGCAAGGAGGGGAGGAAGAAACCGTTCCTCCTGTGGATCTGCAAAGACCAGTC CAAGAGGATTTTAGTGTTAGGAAAAGGAATCTGGAGTGACGAGAAAGGGGGCCTTTCTAG ATGTTGCATGGCTTTGGTGTCGGGAGCCACTTATGGGACAGCAGGTACTCTAAAAAGCCA CCTCCTTAGGAAAGCAGAGAGGCCCTGGCCAGCTCAGGCTCCCAGCAAGAGCTCCTTCTA GGAGACAGCTGAGGGATGAAACACACCCAAGGCTCAAGAGGGGCAGGTTCTTCCCAGATA CAGACCCAGGAAGGAGATAAAGGCTTGGTGCCTCTATTTGGTTCAGGATAAGGGCCCCTG TCCTCTTTCTCTGATAACACTGTCCTCTTTCTCTGATAACACCGTCCTCCCTTCCAGATC CACGTACAAAGGAGGCCCTTAAAAAGGCACTTGGTCATTCACAGCTCAAACTGAGCAAGA GGCTGTGGGAGAAGAATCAAGTTGGTCCCGAGGGGAAGAGGTGTCAAAGGCTTAAGAAAC AAGAAGTCAGAGTTTACCTGGGTTTGAGGGAGAATTTTCTTTCCCCCTTTTCCTCCTCCT CCTCCTTCTTCTCTTTTTTTTTTTTTTTTTTTTTTTTTTGAGACATGGTCTCATTCTGTC ACCCAGCACCCAGGCTGGAATGTAGTGGCACGATCACTATCACGGCTCACTACAGCCTCT ACCTCCCGGGCTCAAGCGATCCTCCTACCTCAACCTCCTGAGTAACTGGGACTACAGGCA CATGCCACCACACCCAGCTATTTTTTTTTTTTTTTTTTGCTAGAGATGGGGGTCTCTACC AGGTTGGTCTCATACTCTTGTACTCAAATGATTCTCCTGTCTCATCCTCCCAAAGGGGTG GGATTACAGGCATAAGCCACCATGCCTGGCTCTTCTTTTGGTTTCAGAGAAAAACATCTC CTTAAAATGTTTATTTCCCAAGGATTCTTGAAAAAGAAAGCTCACTGACACACCCAAAAC AATCTGGTTTTGCTCTGTGCTTTTAGGGAGAACTTTCTAAGCAGCAGAGCCCTTCTGAGT GGCAGGGCTGTCTTAGGAGGAAGGTGTCTTTGATGATGGGGAACTTCATGTCCAGGTCTG GCAGGAGAGTTACCCCACTTTCCTGCCTACTCCCTGGGGCTTTGGGGTAGTAGTACCACA TTGGGCCATGTCATTTAGGTGAGTCCTTCAACATCACTTTCTCTGCTTCTCCCTCTTTCT GGATCCTCCTTCTTGGAGCCTTTCAAGGGGACCTCCTCTCACAGTGTCCATAGCATCTCT TAGCTAATGGTCCTTAAAATCTCTACCAGCAGCTCTCTCTGATAGCTAAGAGCTGCCATT TACTGGGAACTTTCTATGTACTGGGCTCTGTGCTAAGTGCCCTAGATGAGAGATGTGCAG TGTGGTGCCTAAACCTTGGGCTTGGAGCAGACACACACTTTCAAATCCTGCCTTCAGCTC CTTAGTGAACATGTCACCTTGGGCGGGACACACGCCTCTCTGTGCCTCAGTTTCCTACAC TTTAGAATGGGGATAACACTGAATAATGTTCTTGTGAGGATGCAGGGAATTAACCCACGC ACAGTACTTATAATAGTGTCTGGCGCCTGTGTTCGATAAGTTTTAGCAATTCTAATCATC TCTTTTAAGCCTCGCAGCAAGCCTCTAAGGTAAGTCTGTATTAGTATCCCTATTTACAGA TGAGAAAACTGAGGTTCACAGGGGATGAGACAGTGTACAGTCTGCAGTCCAGCAATTACT CTGCTACTCAGCAATAAAAATAGTAACAGCTAACCCTTAGACTAAGTGGCAGAGTCAGGC TTTAGATTCATGAGGTGAGTTCTGGAATCCATCCCTTTAATAACCACACTAAATTGCCTT TCTGAAATGGTTATATAAAGCATATCTACCCAATCTTGGAGTTTTTTAAATGGCACCTAG TTTGGTGCTGGAAATGCAGTTGACCTTCAAAGCAATTCTTTGGAGGCAGCATCAATCCCT CTGGAAATACCTCGGTGGCATGGCTGGCCTTATTCTACAGGTAAGGAACTTGAAGCTAAG CATCAGTAACCCCGTGAAGTCACAGTTAGTATAGGTTGGAATTGGGATTCAAATCTGTAC CTGACTTTATAATTCCTAGCTGGGCCCCAGAATCTTTGATAGAGGTGTCTTCTTTCTTTT CTTTTCTTTCTTTCCTCTTTCTTTCCCTTCCTTCCTCTCTCTCTGTCTTTCTTCTCTCCT TTCTTTCTCACAGAATCAAAATCTCTTGGGGTGGGGCCTGGGCATCTGATTTTTAAAAAC CAGACATCTGATGTGCAGTCAACACTGAGAACCCCTGCCAGCTTCATCTCCTCTTCTAAG TGCCAGACCCAAGTTTCCGACTGTCTGCCCACCTGTCTTCCCACCTGGGCACCCGCCAGC GTCTCACCCTCAGGAGACTCCAGCTGAACTAATCCTCTCTCCCTGCTTTTCCAGAACAGG TCCCACCCTCCCTCCACTCAGTCTCTCCTGCTGGGAACCCTGGTCATCTGCACTGTGCCT TCATCTTCCATCCTGCCAGTGCTGCCCGGTGTGTCTCTTAAACCCATGCCTCCTCTGTGT GCACCACCTGCACTTTGGTAAAAGCCTTCATTTCCTGCTTGGGTTACTACAACGCCCCCT AACTCATCTCACTGTCTCTATTTCTGCTTCTCTGTCTCTCCCTAGGCTACTCCCATTCTT CCTCCCCTTTCCTCTTCATCCCAAAGTCCAACCCATATCCTTTTACCAGTAGGACTTAAG GAACTAAAGACTATCTCATCACCCACTTTTCTTCTTAAAAACTTCCACTGCACTGCCTGC TGAGATGGCCTTCCTACCCAACTTGGCTGGAAAACTCCTACCCATCTTGTGGAACCCAGT TCAAAAGTCACCACCTCTGAGAAGCCTTCCCTGAGGCTCCTAGGGAGATGGGTACTGCCT CCTCTGTCCTTCTCCAGCACAGGCCCCATCTTCAATCACAGGATTGTGCTGGAATGATTG GATGCCAAGTCTGTCCCTCACTGAACTCCTTATGCAAAATCCATATTATATGTTTCCTTT TGCCAGGTGTGGGCCCAGGTGCTGGGGATACCGATGAATAAAACTGAGTTTCTGTCTTCA AGAAGCTCCAAGTCTACTGAGTGTAGCAGAGAACAGGGAGAAGGCACTTCAGGGAGAAGG CGTAGCACATGCAAAGCCCCAGAAGGCAGGGACAGAAGCCTTAGGGATGTCTGTGGGGGA GGATGGAGGAAGAGGGTAACAGGAGACCAGGTGGGGAGATGAGGGAGGTGGTCTGGAAGG GCCATGAGACACCCCTCACGCTCCCTGAGACCCCCTCCACGCTATAGAGATGGGACTGGA GAGGACGATGATCATTTGTGACTCAGATCCCTGTGGGTTTCTTCAGATTGGGTCTCACCC ATCTTTACAGCCACAGCACCTAACACAGTGCCCGGCACACAGCAGGCCCTAGACAAACGT TTGCCACATGAAGTCATGCCCACTGGGCCAGGAAGCCCACTGGGGACTGGGGGGTTGGTT CTGCGATAATGGGGTCCCTGAGATTCTATGTTTCACGTGACTAAGCCTCACTCTGCCCCC ACCTCCGCGGGGGCGTCCCGCAGGTGCCCGACTCCAGCCATGCTGGCGCTACTGTGTTCC TGCCTGCTCCTGGCAGCCGGTGCCTCGGACGCCTGGACGGGCGAGGACTCGGCGGAGCCC AACTCTGACTCGGCGGAGTGGATCCGAGACATGTACGCCAAGGTCACGGAGATCTGGCAG GAGGTCATGCAGCGGCGGGACGACGACGGCGCGCTCCACGCCGCCTGCCAGGTGCAGCCG TCGGCCACGCTGGACGCCGCGCAGCCCCGGGTGACCGGCGTCGTCCTCTTCCGGCAGCTT GCGCCCCGCGCCAAGCTCGACGCCTTCTTCGCCCTGGAGGGCTTCCCGACCGAGCCGAAC AGCTCCAGCCGCGCCATCCACGTGCACCAGTTCGGGGACCTGAGCCAGGGCTGCGAGTCC ACCGGGCCCCACTACAACCCGCTGGCCGTGCCGCACCCGCAGCACCCGGGCGACTTCGGC AACTTCGCGGTCCGCGACGGCAGCCTCTGGAGGTACCGCGCCGGCCTGGCCGCCTCGCTC GCGGGCCCGCACTCCATCGTGGGCCGGGCCGTGGTCGTCCACGCTGGCGAGGACGACCTG GGCCGCGGCGGCAACCAGGCCAGCGTGGAGAACGGGAACGCGGGCCGGCGGCTGGCCTGC TGCGTGGTGGGCGTGTGCGGGCCCGGGCTCTGGGAGCGCCAGGCGCGGGAGCACTCAGAG CGCAAGAAGCGGCGGCGCGAGAGCGAGTGCAAGGCCGCCTGAGCGCGGCCCCCACCCGGC GGCGGCCAGGGACCCCCGAGGCCCCCCTCTGCCTTTGAGCTTCTCCTCTGCTCCAACAGA CACCCTCCACTCTGAGGTCTCACCTTCGCCTTTGCTGAAGTCTCCCCGCAGCCCTCTCCA CCCAGAGGTCTCCCTATACCGAGACCCACCATCCTTCCATCCTGAGGACCGCCCCAACCC TCGGAGCCCCCCACTCAGTAGGTCTGAAGGCCTCCATTTGTACCGAAACACCCCGCTCAC GCTGACAGCCTCCTAGGCTCCCTGAGGTACCTTTCCACCCAGACCCTCCTTCCCCACCCC ATAAGCCCTGAGACTCCCGCCTTTGACCTGACGATCTTCCCCCTTCCCGCCTTCAGGTTC CTCCTAGGCGCTCAGAGGCCGCTCTGGGGGGTTGCCTCGAGTCCCCCCACCCCTCCCCAC CCACCACCGCTCCCGCGGGAAGCCAGCCCGTGCAACGGAAGCCAGGCCAACTGCCCCGCG TCTTCAGCTGTTTCGCATCCACCGCCACCCCACTGAGAGCTGCTCCTTTGGGGGAATGTT TGGCAACCTTTGTGTTACAGATTAAAAATTCAGCAATTCAGTA OMIM ID 185490