Entrez gene ID | | 6653 |
Official gene symbol | | SORL1 |
Full name | | sortilin-related receptor, L(DLR class) A repeats-containing |
Aliases | | ,C11orf32,FLJ21930,FLJ39258,LR11,LRP9,SORLA,SorLA-1,gp250, |
Gene summary | | This gene encodes a mosaic protein that belongs to at least two families: the vacuolar protein sorting 10 (VPS10) domain-containing receptor family, and the low density lipoprotein receptor (LDLR) family. The encoded protein also contains fibronectin type III repeats and an epidermal growth factor repeat. The encoded protein is translated as a preproprotein and likely plays roles in endocytosis and sorting. There may be an association between expression of this locus and Alzheimer's Disease. |
Location | | Chromosome: 11 Locus: 11q23.2-q24.2 |
Gene position | | 121322961 - 121504471 Map Viewer |
Gene orientation | | plus |
Gene size | | 181511 bp |
Gene sequence |
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OMIM ID | | 602005 |
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