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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for SORL1 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID6653
Official gene symbolSORL1
Full namesortilin-related receptor, L(DLR class) A repeats-containing
Aliases,C11orf32,FLJ21930,FLJ39258,LR11,LRP9,SORLA,SorLA-1,gp250,
Gene summaryThis gene encodes a mosaic protein that belongs to at least two families: the vacuolar protein sorting 10 (VPS10) domain-containing receptor family, and the low density lipoprotein receptor (LDLR) family. The encoded protein also contains fibronectin type III repeats and an epidermal growth factor repeat. The encoded protein is translated as a preproprotein and likely plays roles in endocytosis and sorting. There may be an association between expression of this locus and Alzheimer's Disease.
LocationChromosome: 11   Locus: 11q23.2-q24.2
Gene position121322961 - 121504471  Map Viewer
Gene orientationplus
Gene size181511 bp
Gene sequence
OMIM ID602005