Entrez gene ID | | 66596 |
Official gene symbol | | Gtf3a |
Full name | | general transcription factor III A |
Aliases | | 2010015D03Rik,2610111I01Rik,5330403M05Rik |
Gene summary | | The product of this gene is a zinc finger protein with nine Cis[2]-His[2] zinc finger domains. It functions as an RNA polymerase III transcription factor to induce transcription of the 5S rRNA genes. The protein binds to a 50 bp internal promoter in the 5S genes called the internal control region (ICR), and nucleates formation of a stable preinitiation complex. This complex recruits the TFIIIC and TFIIIB transcription factors and RNA polymerase III to form the complete transcription complex. The protein is thought to be translated using a non-AUG translation initiation site in mammals based on sequence analysis, protein homology, and the size of the purified protein. [provided by RefSeq] |
Location | | Chromosome: 5 Locus: - |
Gene position | | 147760233 - 147767190 Map Viewer |
Gene orientation | | plus |
Gene size | | 6958 bp |
Gene sequence |
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