Entrez gene ID | | 6711 |
Official gene symbol | | SPTBN1 |
Full name | | spectrin, beta, non-erythrocytic 1 |
Aliases | | ,ELF,SPTB2,betaSpII, |
Gene summary | | Spectrin is an actin crosslinking and molecular scaffold protein that links the plasma membrane to the actin cytoskeleton, and functions in the determination of cell shape, arrangement of transmembrane proteins, and organization of organelles. It is composed of two antiparallel dimers of alpha- and beta- subunits. This gene is one member of a family of beta-spectrin genes. The encoded protein contains an N-terminal actin-binding domain, and 17 spectrin repeats which are involved in dimer formation. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq] |
Location | | Chromosome: 2 Locus: 2p21 |
Gene position | | 54683454 - 54898583 Map Viewer |
Gene orientation | | plus |
Gene size | | 215130 bp |
Gene sequence |
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OMIM ID | | 182790 |
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