Database of mammalian genes
Home

Home Search Browse Statistics User guide FAQs Links Questions Contribute Download


Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for STC1 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID6781
Official gene symbolSTC1
Full namestanniocalcin 1
Aliases,STC,
Gene summaryThis gene encodes a secreted, homodimeric glycoprotein that is expressed in a wide variety of tissues and may have autocrine or paracrine functions. The gene contains a 5' UTR rich in CAG trinucleotide repeats. The encoded protein contains 11 conserved cysteine residues and is phosphorylated by protein kinase C exclusively on its serine residues. The protein may play a role in the regulation of renal and intestinal calcium and phosphate transport, cell metabolism, or cellular calcium/phosphate homeostasis. Overexpression of human stanniocalcin 1 in mice produces high serum phosphate levels, dwarfism, and increased metabolic rate. This gene has altered expression in hepatocellular, ovarian, and breast cancers. [provided by RefSeq]
LocationChromosome: 8   Locus: 8p21-p11.2
Gene position23712320 - 23699434  Map Viewer
Gene orientationminus
Gene size12887 bp
Gene sequence
OMIM ID601185