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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for STK4 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID6789
Official gene symbolSTK4
Full nameserine/threonine kinase 4
Aliases,DKFZp686A2068,KRS2,MST1,YSK3,
Gene summaryThe protein encoded by this gene is a cytoplasmic kinase that is structurally similar to the yeast Ste20p kinase, which acts upstream of the stress-induced mitogen-activated protein kinase cascade. The encoded protein can phosphorylate myelin basic protein and undergoes autophosphorylation. A caspase-cleaved fragment of the encoded protein has been shown to be capable of phosphorylating histone H2B. The particular phosphorylation catalyzed by this protein has been correlated with apoptosis, and it's possible that this protein induces the chromatin condensation observed in this process. [provided by RefSeq]
LocationChromosome: 20   Locus: 20q11.2-q13.2
Gene position43595120 - 43708594  Map Viewer
Gene orientationplus
Gene size113475 bp
Gene sequence
OMIM ID604965