Entrez gene ID | | 6834 |
Official gene symbol | | SURF1 |
Full name | | surfeit 1 |
Aliases | | ,-, |
Gene summary | | This gene encodes a protein localized to the inner mitochondrial membrane and thought to be involved in the biogenesis of the cytochrome c oxidase complex. The protein is a member of the SURF1 family, which includes the related yeast protein SHY1 and rickettsial protein RP733. The gene is located in the surfeit gene cluster, a group of very tightly linked genes that do not share sequence similarity, where it shares a bidirectional promoter with SURF2 on the opposite strand. Defects in this gene are a cause of Leigh syndrome, a severe neurological disorder that is commonly associated with systemic cytochrome c oxidase deficiency. [provided by RefSeq] |
Location | | Chromosome: 9 Locus: 9q34.2 |
Gene position | | 136223361 - 136218666 Map Viewer |
Gene orientation | | minus |
Gene size | | 4696 bp |
Gene sequence |
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