| Entrez gene ID | | 6844 |
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| Official gene symbol | | VAMP2 |
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| Full name | | vesicle-associated membrane protein 2 (synaptobrevin 2) |
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| Aliases | | ,FLJ11460,SYB2,VAMP-2, |
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| Gene summary | | The protein encoded by this gene is a member of the vesicle-associated membrane protein (VAMP)/synaptobrevin family. Synaptobrevins/VAMPs, syntaxins, and the 25-kD synaptosomal-associated protein SNAP25 are the main components of a protein complex involved in the docking and/or fusion of synaptic vesicles with the presynaptic membrane. This gene is thought to participate in neurotransmitter release at a step between docking and fusion. The protein forms a stable complex with syntaxin, synaptosomal-associated protein, 25 kD, and synaptotagmin. It also forms a distinct complex with synaptophysin. It is a likely candidate gene for familial infantile myasthenia (FIMG) because of its map location and because it encodes a synaptic vesicle protein of the type that has been implicated in the pathogenesis of FIMG. [provided by RefSeq] |
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| Location | | Chromosome: 17 Locus: 17p13.1 |
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| Gene position | | 8066293 - 8062465 Map Viewer |
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| Gene orientation | | minus |
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| Gene size | | 3829 bp |
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| Gene sequence |
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| OMIM ID | | 185881 |
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