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Gene information for ADAM17 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID6868
Official gene symbolADAM17
Full nameADAM metallopeptidase domain 17
Aliases,ADAM18,CD156B,CSVP,MGC71942,TACE,
Gene summaryThis gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biologic processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The protein encoded by this gene functions as a tumor necrosis factor-alpha converting enzyme; binds mitotic arrest deficient 2 protein; and also plays a prominent role in the activation of the Notch signaling pathway. [provided by RefSeq]
LocationChromosome: 2   Locus: 2p25
Gene position9695917 - 9629392  Map Viewer
Gene orientationminus
Gene size66526 bp
Gene sequence
OMIM ID603639