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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for TAF6 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID6878
Official gene symbolTAF6
Full nameTAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa
Aliases,DKFZp781E21155,MGC:8964,TAF(II)80,TAF2E,TAFII70,TAFII80,TAFII85,
Gene summaryInitiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. This gene encodes one of the smaller subunits of TFIID that binds weakly to TBP but strongly to TAF1, the largest subunit of TFIID. Alternative splicing results in multiple transcript variants. [provided by RefSeq]
LocationChromosome: 7   Locus: 7q22.1
Gene position99717481 - 99704693  Map Viewer
Gene orientationminus
Gene size12789 bp
Gene sequence
OMIM ID602955