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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for TCEB1 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID6921
Official gene symbolTCEB1
Full nametranscription elongation factor B (SIII), polypeptide 1 (15kDa, elongin C)
Aliases,SIII,
Gene summaryThis gene encodes the protein elongin C, which is a subunit of the transcription factor B (SIII) complex. The SIII complex is composed of elongins A/A2, B and C. It activates elongation by RNA polymerase II by suppressing transient pausing of the polymerase at many sites within transcription units. Elongin A functions as the transcriptionally active component of the SIII complex, whereas elongins B and C are regulatory subunits. Elongin A2 is specifically expressed in the testis, and capable of forming a stable complex with elongins B and C. The von Hippel-Lindau tumor suppressor protein binds to elongins B and C, and thereby inhibits transcription elongation. [provided by RefSeq]
LocationChromosome: 8   Locus: 8q21.11
Gene position74884346 - 74858634  Map Viewer
Gene orientationminus
Gene size25713 bp
Gene sequence
OMIM ID600788