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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for TCEB3 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID6924
Official gene symbolTCEB3
Full nametranscription elongation factor B (SIII), polypeptide 3 (110kDa, elongin A)
Aliases,EloA,FLJ38760,FLJ42849,SIII,SIII p110,TCEB3A,
Gene summaryThis gene encodes the protein elongin A, which is a subunit of the transcription factor B (SIII) complex. The SIII complex is composed of elongins A/A2, B and C. It activates elongation by RNA polymerase II by suppressing transient pausing of the polymerase at many sites within transcription units. Elongin A functions as the transcriptionally active component of the SIII complex, whereas elongins B and C are regulatory subunits. Elongin A2 is specifically expressed in the testis, and capable of forming a stable complex with elongins B and C. The von Hippel-Lindau tumor suppressor protein binds to elongins B and C, and thereby inhibits transcription elongation. [provided by RefSeq]
LocationChromosome: 1   Locus: 1p36.1
Gene position24069856 - 24088549  Map Viewer
Gene orientationplus
Gene size18694 bp
Gene sequence
OMIM ID600786