Entrez gene ID | | 7006 |
Official gene symbol | | TEC |
Full name | | tec protein tyrosine kinase |
Aliases | | ,MGC126760,MGC126762,PSCTK4, |
Gene summary | | The protein encoded by this gene belongs to the Tec family of non-receptor protein-tyrosine kinases containing a pleckstrin homology domain. Tec family kinases are involved in the intracellular signaling mechanisms of cytokine receptors, lymphocyte surface antigens, heterotrimeric G-protein coupled receptors, and integrin molecules. They are also key players in the regulation of the immune functions. Tec kinase is an integral component of T cell signaling and has a distinct role in T cell activation. This gene may be associated with myelodysplastic syndrome. [provided by RefSeq] |
Location | | Chromosome: 4 Locus: 4p12 |
Gene position | | 48271814 - 48137800 Map Viewer |
Gene orientation | | minus |
Gene size | | 134015 bp |
Gene sequence |
| |
OMIM ID | | 600583 |