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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for TEF (Homo sapiens) (Information is obtained from NCBI Gene database)

Entrez gene ID 7008 Official gene symbol TEF Full name thyrotrophic embryonic factor Aliases ,KIAA1655, Gene summary Thyrotroph embryonic factor (TEF), a transcription factor, is a member of the PAR (proline and acidic amino acid-rich) subfamily of basic region/leucine zipper (bZIP) transcription factors. It is expressed in a broad range of cells and tissues in adult animals, however, during embryonic development, TEF expression appears to be restricted to the developing anterior pituitary gland, coincident with the appearance of thyroid-stimulating hormone, beta (TSHB). Indeed, TEF can bind to, and transactivate the TSHB promoter. It shows homology (in the functional domains) with other members of the PAR-bZIP subfamily of transcription factors, which include albumin D box-binding protein (DBP), human hepatic leukemia factor (HLF) and chicken vitellogenin gene-binding protein (VBP); VBP is considered the chicken homologue of TEF. Different members of the subfamily can readily form heterodimers, and share DNA-binding, and transcriptional regulatory properties. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq] Location Chromosome: 22   Locus: 22q13|22q13.2 Gene position 41763392 - 41795330  Map Viewer Gene orientation plus Gene size 31939 bp Gene sequence >TEF:21153961..21185899:Length=31939 ATTGGCTGCCTCAAGGCTCCCACCCCGCCTGCCTCCCTAGCCTGCGGCTGGCGGCCCCTG CCTCTCCAGCTGCCTCTGAACTCCCTGGAGCAAGCACCTCCTGCTGGGCTGTGTGAGCTG CGACTGGTTCTCAGTGGCCCCTGCCATGGACATGCCTGAGGTCCTCAAGTCCCTGCTGGA GCACTCTCTGCCTTGGCCAGAGAAGAGAACAGGTAGGAGCACAGGTGACCTGCATTGATT GGCTGCCCAGGTACTCGAGGGGGCGAGGGGGCAGCCACAGGCACAGTGGCAGGACAGGCA TCTCCAAGCCAGGGAGGGTCTCAGCAGTGGTGCGCCCTTGGTCTCAGGGTGCAGAGTGCG GAGAGGGGTTCGAGGAGGCATGTGTCACACCGGCTCTGGGACTCTCTCCTAGGCCTGCTG GATTTGGGGAAGCCATGGCCAGTGTGTGGCCACTGACAGGTGCTGTGCTCATGTGGGACC AGGACAGGACAGGGGGTCCTATTGAAAGAATCTGGCTGGATGCTGACTGCTTTTGAAGCT CCCTCCCCCTGTACGCTGGGGGTGGCAGAGGAGCGGCAGGGACTGTGGATTTGGGCAGCA GGAGCCTGGGTCTGAAGCAGAGGCTTTCCTTGGTGCGCCTGCTGCAGCTCCCGCTTGCCG GAGGGCTGAACTCATGGATGGGATGGAAACTGTTATGTAACAGGACCACAAGGCTCGAAG CCCTGCGTTCCTAGGATACCACAGGCAAAACGCGCGAGGGAGGAGAGAGGAGGGCGTGGA CTGAGGGGCAGACCTGGTGGCCAGCACCAGGTGTCTCCCAAGTCCTGCCTGGGAACCCCA TGGCCAGATTAGTTTGGCGGAGAATACTGATAAATCTCTCTCCAAATCTCTTCTGTTCCC AGAAGTCAGAGGTCACCCCCAGGTCCCCAGGGCTCCAACTCCTCCTTGCCTTTAGAGGGG CCCAGCTGGCTTTTGCTGCCTGAGTCTGACTTGAGCACCTGGGGTGTCCTCTCAGGGGAC CTTTCTCAGGCCTCCCTCTCATCCTGCTGTGCCAGCACCTGCTACCTAGCATCACCAGGT GGCCCTGGTTGTCCCCGCAGGACTCCTTCCTTCCACAGGACGCTCTCAGCCCACTCCCAA ACCAGAGCCAGGAGACAGATCCCACAGCCCCCGGCCTCCCTTCACCCCTCTGGAACTGGG TGTGGGTTTGCTTGGGCTAAGCCAGGAAAGGAGGGTCAGCAGGTTCTAGCCCCAGGGAGA CATTGCCCGAACGGGGAAGGACGTACTGGGAGCTTAGGGCAGGGGCTCCGGAGCTCTCGC ACGCAGCTCTGGGCTCAGGCCCCTCCGACCACACTCCATGCTGTCAAATGGTGGGACAGT CCAGGCCACCCTCTGAGAAGAGTGTCACAGAAGGCGCTCCTGTGGCCTCCTAGCACTGGG GACACCAGTTGCTCACCATGAGAAGCCCACCTCCTCAGCGAAGCCCTCTGCAACTCAGCC GGAGGGATCTGCCCCCATTTGGAGTCCACACCCACAAACAAGCCACAGCTGACTTTTTTG GCATCTCTGAGTGGCCTGTGTGGGTGGGCAGAGCTGAACACATTTCCAAAAGCTAAGGTA GAGGGTCCCCTCCTTGGTCCAGGAACCCAGGAAGGGTGGTACAGTCCCTCCTGGCTCCCC CAAGGTGTCCCAGGATGCCCCCCAGCACACACATGAAGGGCGAGGCTGCCAGTGGGGCAG GGAGGATTCTCAGGGGCGACTCGGGGCACTGCTCCTCAGATGAGGATAACAAGGCCTTTG AAGTGTGGCAGCAGCTGCCGGTCTCTGGCTCCCAGCTGGTCTGTGGGGCCCTGCAATAGC CGAAAAGTCCCCCTCCCTCACTGTGGATGAGCAAAGTCAGGGCCTGGCACATAGGGGACC GCCCAAGGTTTCAGGCAGAGCTTTGCCGAGCACTGGCAAGCTGTGGCCGAGAATTAGTTA GTCCAGCATGGCTGGGCAGGTCCAAGGGGTGTGGGCCAGTCTTGGGTCACCTCCTGTCAC TTCATGTGGCATCTCACTGAGAGTGAGAAGCATGAGGTCCCACAGGACCGACAGATGCCA GCAGCCAACTGCTAGATAAAATGAGGGGAAGAGGGCTGAAGAGCCACAGGACTCACAATG ACTGCAGCACATTACTGCCCCCTAATCTGCAATCAGTTTCCCAAAGCTGCCCGAATCTCC AGACCATTTATAAACAGAAACGTCTACCTGAAAAGCAATAGACCTTGTTGAAAAGAGGGT ATAGCCACCACACAGAATGATTACAGAATTACTTGCCATCAGGGACCATGTACTTAAGTA GTTGTTGAAGTGGCTTCTCTTCCATCTGCCACTGCTCTGACTCTGGGTGTGAATTGGAGA AAGACAACAGAGGCCAGGTGCTCCAGAAAACAGGGATGCCCTCAGGTCCGCGTGCCCTTG CTTTGGTGGACTTCCTGCTGCTCCCGTCCAGTGGAAGGGGGCAGTTATCTCTTTGGATGA CTGTTTACAAACTCCCCATTTTCTCTTCTTTCTCCTGCCCAATGGCTGTGCTTCGGCACA CATTTAGGTCATGTGCAGAGCGTATCTCACCTCCAGTGGGAGGGAAGTGTACAGGAAAGT CTGCGGAGTGTGAGAAACTCCAGGTGTGCTCTCCCCATGCTCTCCGCTCCGTGCAGCCTC TCACTCCACTTTCTTTTATTTTCTCTTTCCCCCTTTTTTTTTTTTGAGATAAGAGTCTTG CTCTATCGCCAGGCTGGAGTGCAGTGGTGCTATCTCGGCTCACTGCAACCTCTGCCTCCT GGGTTCAAGCAATTCTCCTGCCTCAGCTACCCGAGTAGCTGGGACTACAGGCGCCCGCCA CCACGCCAGGCTAATTTTTGTATTTTTAGTACAGATGGGGTTTCACCATGTTGGCCAAGA TGGTCTTTATCTCTTGACCTCATGATCCGCCCGCCTCAGCCTCCCGAAGTGCTGGGATTA CAGGTGTAAACCACTGCGCCTGGCATTTTTTTTTTTTTTTTTTGAGCCAGTGTCTCACTC TGTTGCCCAGGCTGGAGTGCAGTGGTGCAACGTCAGCTCACTGTAACCTCCACCTCCCGT GTTCAAGCAATTCTCCTGCCTCAGTCTCCTGAGTAGCTAGGATTACAGGCACCCGCCACC ACGCCCGGCTAATTTTTGTATTTTTAGTAGAGACAGGTTTCACCATGTTGGCCAGGCTGG TCTCAAACTCCTGACCTCCAGTGATCCAGCTGCCTCAGCCTCCCAAAGTGCTGGGATTAC AGGCGTGAGCCACTGCACCCAGCCTCATTCCGTTTTCTAGTTCATTGATGCCCCTTGAAA CCCAGACTTGGGGTCCCTCTCCCTCGTGCTGCCCCTGGGCCTCCCAGCCCAGCCCGTGTA GACCTTGCCTCTTTCCTGTCCCTGGATAAACAGACTTTCTCCACCAGAGCTGACCAGCTC CCAGACTCCCTTGGCTTCCAACGACAATGGCTTCTTGGTGGCCTTCACTCTAGGCCATGA GTTCAAACAATTTCTCTTTTGGCAGAGAAATCCATTTCCAGCAAAAGGGTGGGTCTGTAG CCAAGCCCTGACTCAGTTTCCCCTCTATGTCCCTGGGCCCTAAATCCTGAAAACCACTCT TCCTGTCTTCACTCCCAACCTGTCTCCCAAGGATACTTTTCCAAGAGTTGATTCTGTTCC AGACTGCTCACTCCAGCTCTTAACGTCTTTCTCTTCCAGCTTCTGGAAAGACACTGTGTC TCTAAATCATATGATTAGCATTTTATACCCTATACTTCCCTCTCCCATGGGGCCCTGGCC ATGCTTAGAGACACCTCCTCCCATTTTCTTGCCATCTCCGGTCACTCAGGCCTCCGTTTC AGGGAGTTGTGAAGCCGGAACATACACCTCAAAGGCTGAACAAGGCCTTTGCTTTGGGCT GGGCAGGCGGCATCCCCACGTAGGGGCACTCCTGATCTAGAATCCTTTCTAGGCAAGGCA GTGTGGCCCTGGGAAGAGAGCAGGGGGCTTATGATCAGAGTCAGGCCACAAATCCTAATT CTACAACCCACTGGTTGGGACTTGCCCCCCTCTCTCTCCATCTCCAGACTTTAAAAAGCG GAAAAGAATATCTGTGCCATGAGCTTGTTGCCAAGATTAAGTGAGTTATCCCATGTGAAA GTGTCTGCAAACCGTGAGATGCTGTGCTGGTTTTTTCTGTGAAAGGCAAACAGCAGCATG GCCTGGCGTCGTGCGTCTTCCACCTACATCCCATTTGCAACCTGACCCTCATTCCCTTCT TTCCACCTTCCTTTGAAGAACTGGATGGTACAAGTTGGTGTGTACACACACACACACGGC TGTCTCCTTGGAAACACATGCTGAGGCTCCTAGAGGCATGGTGCCATCTGCCCTGCACCC AATGGGACAGCCCCATTTCATAACAGGCAGGATCTCAGTAGGACTTGCTGGGGCAGAGGC AGGGGTACAGGAGGGGGCCTTGGTGTCATCCTCTTGGTGGACTGAGGGAAATGAGCCGAG AGTGTGGACTCGGTGCAGCCTGGGCTCTCCTGAGCTTGGCCTGAGTGAAGGGCCCTGTGT TTGCCTCCATGCACAGCCTGGGAACCAGAGCAAAACTGAGAAATCGAGGAGTTTGCTTTC AGGGACGAGGATGGGGAGAGGGCCTTCTATGTGCTGGATATGCTAGCTCATTTAATCCTC ACTGCCTCTTTCTAAATGGTATATTTCCCCTGTTATTCTGGTGAGAAAATGAACAAAGAG GCACTGGCTACCCTCAGGGCCAGTCTCTCTCTTCTTCCTTCCCACCCTAGGTGCCCAGAG CCTTCTTCTCTACCTGCCCCCCACCCCATCCCTTCAGAGAAATGTGAGAAACTCATTCTT ACCAAGTGCCAGGCATTGACGGCATGTCGAGGAGTGATCCTTCCAGATGGCTAGGCTGCT GCAGGACGGGCTCCTGACTTGACAGCCACTGTCTCCTGAGCGTGAGCCAGGACTGTATTG TGTGTGCCTATGTCACTATCTGTGCAATGGCTCTGCAAGGAAGGTATGATCATCCACTCT ACGAATAAGGACATCGACGCTCAGAGAGAGGAAAGGCCACACAGTTGTTGAAGGATTCAA ACCCAGTTCCTCCTGACACCAGGCTCGTGTCTACCCATAGGGTGGGTACCCATGTGGGTA CCATGTCTCGGGTCGTAGCTCTTCGTCACCCAGCCACTCATCACGTGCTTCCAGAGCGTT TGCTATGCTTGGAGAGCCCGGGGTGAATGAAACCAACTCTACTCTTGCTCCCCTGGTGTT TGGATTCTAGAGGGGAGAGAGAATCTGCTGTGTTTAGGCAGGAGGCGGTGGTGGTCAGGA CCAGCCTCTCCCAGGGAGAGGCATTTGAACTGAGGCCTGGAGGCCTGGAGGGTGAGGAAG AGCCAGCTACCCGAGGAACTTTCAGGCTGTGGGAAGAGCACCTGCAAAGGCCCTTCCTGG GACAGGAAAGAAAACGGGTCTGAGGAATAAAAGGCCACCATGGCTGCAGAAAGCAAGCAA GGGGGAGAGGGGTACCAGGTGAGGCTGGAGAGACCCGAAGGGCGAGCACCTGCAGAGCTT TGACGGTCATAAAGAGGAGTGACGCTCTCATCTCCCTGTCTGTAAGGACCCTCACACTCA CTATTCTTGGGGAAGTGGCTGGTGGGGAGAAATTAGGTATCCCCAGAACAACCCAAGCAG GAATTACAGTAGAGTTAACTTTGACCGAGCACATGCTATAGGCCAGGTGGTGTCCTAGCA CTGTGCCTGAATGGACTACTTTACTTCGGACACCACGGTACAGAGAAGTTCAACAATTTG TCCAAGGTCACCAAGAAATACAGTTAACCCTTGAATACCACAGGGATTAGGAATGCTGCC CCGCCATGCAGTAGAAAATCTGCATATAATTTTTGACTCCCCAAAAGCTTAACCACTAAT AGCTTATTGTTGATGGGAAGCCTTACAGATAACATCAACAGTCCATGAACATATATTTTG TATGCTATATGTATTAGATAGTATATTTTTCTTTTTTTTTTAGACGGAGTCTCACTCTGT CGCCCAGGCTGGAGTGTGGTGGCGTGATCTAGGCTCATTGCAACCTCCGCCTCCCAGGTT CAAGCAATTCTCCTGCCTCAACCTCCTGAGTAGCTGGGATTATGGGCGCCCACCACCACG CCCAGATAATTTTTGTATTTTTAGTAGAGACGAGGTGTCACCATCTTGGCCAGGCTGGTC TTGAACTCCTGACCTCATGATCCACCTGCCTTGGCCTCCCAAAGTGCTGGGATTACAGTC GTAAGTCACCACGCCCGGACTTTTTTTTTTTTTTTTTGGAGACGGAGTCTCCGTCACCCA GGCTGGAGTGCAATGGTGTGGCCTCGGCTCACTGCAACCTCTGCCTCCAGGGTTCAAGCG ATTCTCCCGTCTCAGTCTCCCGAGTAGCTGAGACTACAGGCGCATGCTACCACACCCGGC TAATTTTTGTATTTTTAGTACAGACAGGGTTTCACTATGTTGTCCAGGCTGGTCTGGAAC TCCAGACCTCATGATCTGCCTGTCTCAGCCTCCCAAAGAGCTGGGATTGCAGGCATGAGC CACCGCGCCCAGCCTATATACTGTATTCTTACAACAAAGTAAGCTACAGAAAATAAAATG TTATTAAGAAAATCATGGCCGGGCGCAGTGGCTCACGTCTGTAATCCCAGCACTTCGGGA GGCTGAAGTGGGAGGAGTGCTTGAGCCCAGGAGTTTGAGACCAGCCTGAGCAACATAGTG AGACCCTGTCTCTACCAAAAAAATTAAAAATTAGCTAGGCAAGCCAGGCATGGTGGCTCA CGCCTGTAATCCCAGCACTTTGGGAGGCCGAGGCAAGTGGATCACAAGGTCAGGAGATCG AGACCATCCTGGCTAACATGGTGCAACCCTGTCTCTACTGAAAATACAAAAAAAATTAGC CGGGCGTGGTGGCGGGCACCTGTAGTCCCAGCTACTCGGTAGGCTGAGGCAGGAGAATGG CGTGAACCCAGGAGGCAGAACTTGCAGTGAGCCGAGATCGCGCCACTGCACTCCAGCCTG GACAACTGAGCAAGACTCTGTCTCAAAAAAAAAAAAAAATTAGCCAGGCAAGGCAGTGCA CACCTGAAATCCGAGCTACTCTGGAGGCTGGGGCAGGAGGATTGCTTGAGACCAGCAGTT CAAGGCTGCAGTGAGCTATGACAGCATCACTGCACTCCAGCCTGGGGGACAGAGCAAAAC TGTCTCAAAAAAAAAAAAAAGAAAAGAAAATCATAACAGAATCTTAACTAAGTTGAAGTG GATCATTGTAAAGGTCTTCAGCCTTGTCTCCATATTGAGTAGGCTGAGGAAGAGGAGGAG GTGGAGGAAGAAGAGGGGTTGATCTTGTTGTTTCAAGGGTAGCAGAAGTTGAAGGGGAGG CAGGAGAGGCAGGCAAATTTAGTGTAACTTTTGTTGAAAAAAATCCACATGTAAGTAGAC TCATGCAGTCCAAACCCCTGTTGTTCAAGGGCCGACTAAAGTGGAAGCAGGAGTCAGCCC CAGGGGGTCTGGCTCCAGAGGCCCACCTCTGTCCCCTCCAGCACGTCTTTGACTGCAGAA ACCGTGGCTATCTGGTAGTGGCTTCTGAGACATCACACAGGGCAGAGGTGAGGGCTTCTC TCTGGAAAGGGCACTCTTGAGGGAGCTCTCCATTTGCAGACCAAGCCCTGGTAGCGGACA GAATGCAAGACAAACAGGAAACTAGCACTTTTGAGAGTACTGACGAGGAGGGCAAGAATC AGTAAAGAGCCTCCACCCACCACTTCTCCCCTGGAACACACTGAGACCAAGGAGGGTACA AACCACAGAGCCCAGGCACAGGTATGTGGGCTAAAAAGGAGAGCTGCTGGCAAGGCTTGT GCGGGCAGACTTGCCAAAGGATGGCTCATGTTTGCTGTTCCAGGTTCAATTGTGAATCAA ACACAATGCCTGTTATTTGATGTTATTAATGCTCCAAATGCGGCCGGGCGTGGTGGCACA CGCCTGTAATCCCAGCACTTTGGGAGGCCGAGGCGGGCGGATCGCGAGGTCAGGAGATCG AGGCCATGCTGGCTAACACAGTGAAACCCCGTCTCTACTATAAATACAAAAAAATTAGCC GGGCTACTTGGGAGGCTGAGACAGGAGAATGGTGTGAACCCAGGAGGCAGACCTTGCAGT GAGCCGAGATTGCGCCACTGCACTCCAGCCTGGGCAACAGAGCAAGACTCTGTCTCAAAA AAAAAAAAAAAAAATTGCTCCAAATGCATATCATTTAGCTCTGAAAGGTTTGGTTAACTG TCCTACTAGTACCAAGAACAAAGCAAGCCAACAAATATTTACTGATAGGGTGGGGATTTT TTCAAAAAAGAGAAAAAAGTATATTTTTACTGGGTTATTACCCTGAACAAAGCATCGTGC CCTCCTGCATTTGATTTGCGCAAAAGACACAGATAACCGGGCTTTCTTAGAGCTCAATGG AAGAAGCCTTATCACCCTCCTGCTCTCACACGTCCCAGGCCCATGTCCCATTTTCAGTAA GCCAGAAAACAGAGTGGGACTGTTCTACTAGGTGCGGAATATATGGCCAAAGAGATCATT ATAGGGTATCTGGCCAAAGGCTCCTGTGTTGGAGTTTTAGCTCCTCTAAACTTCAAGTTT AAGTAAAAATAATCCAAATTGGCAAAATGGCTTAATGAAAATCACTTGTTCTGCTTATGC TCTACTGAACGAAGTTTTTGTTCTGTTTTTGTTTTTTTGTTGTTGTTGAGATGGAGTCTC GCTTTGTGGCCCAGGCTAAAGTGCAGTGGCGCAATCTCGGCTCACCGCAACTTCCGCCTC CTGGGTTCAAGTGATTCTCCTGTCTCAGCCTCCAGAGTAGCTGGGATTACAGGTGCCTGC CACCATGCCCGGCTAGTTTTCACAGAGATGGGGTTTTGCCATGTTGGCCAGGCTGGTCTT GAACTGCTGGCCTTAAGTGAGCCATCCGCCTCGGCCTCCCAAAGTGGTGGGATTACAGGC TTGAGCCATCGTGCCAGGCCTGAACAAAGTTTTTAACTTGGGCTAGTTAGCAGGTTTCTG GAACAGTCGTGACTAGAATTTACAGCCAGTCGTCCAGCTTTGGAAAATGGACATTTCACA TCCAATCTTGTCTGTAGCTTAGACTCTAAACCCACCCTCAGGCCCACAGCCTTGTCCTCA CACACAAAATAACTACTCCTGACCCAACACAGCTTGAACGGAAGGGGAAGGGTGGGTACC CACCCACTCCACACTGCACACCGTGCCAGGCGGGCACTTGGCATTGCACATCACAGGTCA TCCTCACAACCATCCTGTGAGGCGGGCGTATCCATCTCTGTTTCCAAGGCGAAAATAACT GAGGTTTAGACAGGAGAAGTCGCTTGCCCATGGCCATGTGGCTGGGTCAGAAACTGAGGA AGGCCTCCCCACAAAGTCACTGCTGCCCCAGGACCCATGCTTCCCTAAAGAAACCAGTGT GGTCTTGTTTCTTGTTTTTGGTTTTTTGGAGACAGGGTCTCTCTCTGTCACCTGGGCTGG AGAGCAGTGTGGTACAATCACAGCTCACTGCAGCCTTGATCTCCTGGGCTCAAGCAATCC TCCCACCTCAGCCTCCTGAGTAGCTAGGGTACAGGCGCACCACCACACTCAGCTAATTTT TTTTTCTTTGAAAAAACAGAACGCTTCACGAATCTGCATGTCATCCTTGCACAGGGGACA TGCGAATCTTCTCTGTATCATTCCAATTTTAGTATTTGCGCTGCTGAGGCAAGCACATCA GGCTAATTGTTTACTGTTTGTAGAGATGAGGTCTCACTATGTTGCCCAGGCTGGGCTACT GTTCCACACCATACCTTTATTTTTCTCTTTCTCTTTTTTCCCCCTGAAAAGCCTCTCTAA TCTCTCAGCCTTTAAAGTCTTAATCGTGTAATAACATGTTCTTCTTATGGGGTTTATTTC TTTGTCGGGCTCACAAACTATGGAAATTAGCTAACTAGTTCTCCCAACGTTTATTCCTCC ACTAAGACGGGGCAAGGTCACACCAATATTCCCACTTTAGTGATAGGAGACAGAGGTAGA GAGAGGCTGCTGTGGTGGAGAATGAAGAGGAGAACATAATAGCTCCCACCTCCAGGATGG CACTGTTTAATGCTGTAAACTGATGTAGCTAACCCCTCACAGCTGGCAATTAAGCACGAT AGAGAACGTGTTTGCAACGCTCCTGCAGTATTTGTGACACATCATCTACCCTCTGGTTAT CCAGGGGAAAAAACTCTCTCTGGGGAGTGTCAGTACATGAACACCAAGTTCTGGAGGCTT AACCCGCTGGTCTCACTTCTCACCAGCGTCACTTGCCTGTTAGGGTAGCTGCTCCAGGCT GGGAGATGAGTGGAGTAGGCATTATTCGTTTTGGATAACTACAGCTAAAAAAAGAAAATC TAAATCTTTACTTCCTCTTACTACATCCCATCTTTCTCATAAACACGTGTTAGAACCTTC CACTGTTATCATTAATCATTGTCTAATACTTTGAGAATGGGTTTTTCTTCCCAGCAATAA TGTCGTATTAGCCATGAGACTATATAGGTATGATTCTAAGCCATCAAGTCTCCTCATGGC CAAACTAGCAGGTTTTTTAAAAAGCTTCCTTAGCTTCCTTTTTTTTTTTTTTTTTTTTTG AGACAGAGTCTCATTCTGTCCCACAGGCTGGAGTGCAGTGGCACGATCTCGGCTCACTGC AACCTCCGCCTCCCACGTTCAAGCAATTCTCCTGCCTCAGCCTCCCGAGTAGCTGGGATT ACAGGCACTCGCCACCACGCCCAGCTAACTTTTGCCTTTTTTTTTTTTTTTTTTTTGAGA GGGAGTCTCGCTCTGTCGCTCAGGCTGGAGTGCAGTGGCGTGATCTCGGCTCACTGCAAG CTCCGCCTCCCGGGTTCACGCCATTCTCCTGCTTCAACCTCCCGAGTTGCTGGGACTACA GGTGCCCGCCACCACACCCAGCTAATTTTTTGTATTTTTTAGTAGAGACAGGGTTTCACT GTCAGCCAGTATGGTCTCGATCTCCTGATCTTGTGATCCTCCCGGCTCGGCCTCCCAAAG TGCTGGGATTACAGGCGTGAGCCACTGTGCCCGGCTATATTCTTAATAGAGACAGGGTTT CACCACGTTGGCCAGGCTGGTCTCGAACTCCTGACCTCAGGTGATCCGCCTGCCTCAGCC TCCCAAAGTGCTGGGATTACATGGGTGAGCCACCACGCCCAGCCCTGTATTGGTTTAATC AGTTTCCTTGGAATGTCCTTTGTCTAGGTTAGCTTCCCCTAAAGGTGTTTAAGTTTCGCC ACACACAGAATTCTCACTAACAATTCTACAACACAACAAATTTTCTGTACACAATTAACT ATTTTCACTACAGAGAGTGACACAGGCACCACACTAACCTCTGGGATAATGGATATGCCA ACCAGTTTTAGTAAAATTATGAAAACTAAATTTGTTGAAGGTTTGCAACTGTGCGCCTAC GCAAATTGGCTCACAGAAACCCCGTAAGGTAGGCCAGGCGCGGTGGCTCACGCCTGTAAT CCCAGCACTTTGGGAGACGCGGGTGGATCACCTGAGGTCAGGAGTTCGAGACCAGCCTGG CCAATGTGGTAAAACCCCGTCTCTATAGAAAATACAAAAAATTAGGCGGGCACGGTGGCG GGCTCCTGTAGTCCCAGCTACTCCGGAGGCTGAGGCAGGAGAATGGCGGGAAGCCGGGAG GCAGCGCTTGCAGTGAACCGAGATCCCGCCATTTGCACTCCAGCCTGGGCTACAGAGTGA GACTCTGTCTCGGAAAAAAGAAAAAAAAAATTAGCCGTACGTGGTGGTGCACGCCTGCAA TCCCAGCTACTCAGGAGGCTGAGGCAGGAGAATCGCTTGAACTCAGGAGGCAGAGGTTGC AGTGAGCCGAGATCCCGCCATTGCACTCCAGCCTGGGCAACAAGGGCAAAACTCCGTCTC AAAAACAAAAAACAAAAAACAAAAACACCATAAGGTAGAGCCTGCCCTAACTCCATTTGG CATAAAAGGAAAAAACGCTGGGTGCGGTGGCTCACGCCTGTAATCCCAGCACTTTGGGAT GCCGAGGCGGGTGGATCACCGGAGGTCAGGAGTTCGAGACCAGCCTGACCAACATGGAGA AACCCCGTCTCTACCAAAAATACAAAATTAACCCCGTCTCTACTAAAAATACAAAATTAG CCGGGCGTGGTGACGCATGCCTGTAATCCCAGCTATTCGGGAAGCTGAGGCAGGAGAATC GCTTGAACCTGGGAGGCGGAGGTTGCGGTGAGCCGAGATCGCGCCATTGCACTCCAGCCT GGGCAACAACAGCAAAACTCCGTCTCAAAAAAAAAAAAAAGAAAAAAAGAAAAGAAAAGA AAAGAAAATAAAAAGAAAAGGAGGCCTGAAAAGGTAAAGCAATCGAGGCATCAGATTCAG AAAATGACTGAGGTTCAATTACAGTGGCAGTGAGAGCTTGAATTTTGGAATCAGACCTAT CATCCTGTCTCTACCACCACCCAAAGTCCTTCAAATCTCTTGCTTTCCAGGCCTGGTCAG CTACCCAACTTCTTTTTCCTCCTTACCCCGCCGCAAAATTATTTTTATTTATTTATTTTT TTGACATGGAGTCTCCCTCTGTCGCCCAGGCTTGACTGCAGTGGCGCGATCTCGGCTCCC TGAAACCTCCACCTCCCAGGTTCAAACCGATTCTCGTGCCTCAGCTTCCCCAGTACCTGG GATTACAGGCGCCAGCCACCATGCCCGTCTAATTATTTCTGTACTTACAGTAGTGTCGGA GTTTCGCCCTGTTGGCCAGGCTGGTCTCGAACTCCTGACCTCAGGTGATCCGCCACCTCT GCCTCCCAAAGTGCCGGGATTACAGGCGTGAGTCACCAAGCCCAGCCCCAGCAAAATTCT GATTGCATCAGCTTGATAACTTTTAGCTGGCTGTGGGTGTCTGGATCATGCATCTACCCC CTGAACCAAGGACTATCACTATACCACCCCCCCAACCCCTCCTGCTAGAAGGGCTGGGCC ACTGTAGGGATGCTGGATAAACAAGCCAAGCTCTCTGCCTTCCGGGAGTTAAGCGGGGAG TCTAATGTTGCCTGGGTTTGCAGCGGAGTCTGATCTGTACTATAAAGAGGTACAAAGTTC TGAGCGCTGTTTAGGAGCAGCTTTCCATTTGTGTACCGCGCCACATATTACATTTTTACG GATTTCTGCGGAACTCCCGGGGAGGCTTTATATTTTAAGAGAGGAGGTGGTTCTCCCACA AAACGTGGCATCGGTACCTGGTGTCAAGGAGGTTTTTGTTTTCTAGGTAAAAGAAGGGAG AGTTCTAGAAAGGAAAAGAATTTCACATCTGTTTGGGACTGTGGAGATTCTCTAGCCCAA CCTCTTAATTTTATGGCCGAGGAAACAAGCTCCAGTGAAGCAACCGGACTTTCCCAAGGT CATAAGCTAGTAAGTGGGAGGGCGGAAACATGTACTCGGGCCCTGGCTCAGGTCAGAGCT TCAGGAATGCTCCCTCCACGCTAGTGTTGATCTGGATGCGTGGGCAACCCGACACCCCGC TCTAGGGCGGCCAAGCCTGCTCAGGCCATCCCTACGACTTGGCAGGTCGCGGTCCCCGGC CCTGCCCTCAGGCGACCTCTGGGTCGCGTGGGAGCAGAAGTGCGGGCTAAGCTCAGCGTC CCTGCCCCGCGACCCTGGGCAGAGTCCCCAGAACAAAAAGACCCGTCCCTCCCTTCCCCT CCCGCCCCGCCACAGCCCCGCACGTGCGGCGCCTCGTGCACCGCCCCGGGCCCCGCCCCC GCCCTCCATTGGCTGTTCCCGCGCCTTCCTCCTCTGCCCCCTCCCCCCGCGACCAGACTC GGCTGCGGCTCCACGTGACCCGCGGGGGGTGGACACGCCGCGCGAGCAGGAGCTCGGATA GGTCGCTTTGGCCGGCCTGGCCGCTCCGAGCTCCGCCCCTCTTCGGTGGCGCGTCGGGAA GGTTGCAAGTCGGGGACAAGAGGGAGAGGCTGCGGTGGTTGGGGAGGGCGGGGGTTATGA AGAGGGCGGTGAAGGGGGAACACTGGTAGGAGGGAAGGGACCGCGCCGAGGAAGGCCCAC CACAAAGACTCCAGCAGGCGCCAATCAGGGGACACAGGGGCGGCGGGGCGGGGCCTCCGC GAGGGTCCTCACCTGGCCCCGCACGTGTCTATCTTATCCCGGCTGCCCGACCAATCACGG CCCGAGGATCTGCGCCTGCCCCTCTCGCAGGCTGGACCAATCCAGAGCAACGATCCGGGG AAGCTGGCCTGGCCTCATGAATAATTAATGTGCCAGAGCCGGTCCGCAGGCGGGGTAGCG ATGGAAGGAGGCGGGGGCGCCATTGGGCGCCTGCGCAGTAGCTGCCCGTGTCGGCAGCTG CAGCGGGTCGCACGGCTCCGGCCCATCTCGGGGGGCGGGCGGGGGAGGCGAGGTGCGCGA GCCGAGTCCGGGGCACGATGTCCGACGCGGGCGGCGGAAAGAAGCCGCCTGTGGACCCGC AGGCAGGACCCGGTCCGGGGCCGGGGCGCGCAGCTGGGGAAAGGGGCCTGTCGGGGTCCT TCCCCCTGGTCCTGAAGAAGCTGATGGAGAACCCCCCGCGCGAGGCGCGCCTCGGTGAGG GCGGGGGGGTGGTCCGCGCGGGCTGGGGGCGGGGCTTATACAGGGGCGGGGCCTCGTGAG GGCGGGGCCGGGGAGGCAGTGGGTCAGGGAGCAGTGGTCCAGCGGAGGGGGATGGGGCCT GGATGACCAGGAGCCTGGAGGACGAGGCCGGGGGGCTGAGGACAGAGGGTCAGGGGCGGG CTGAGACGGTGGGTCTGGCGGGAGAGGGTGGGGAGAGGTTTTGAGGAGGCGGAAGGGGAT CGGGAGCAGTCACTTAAATGACGCTCCAGGGCCCCTCCCCCGGGGCCACCTGCATCGGAG TCACTCGGGATGCCTGTTTAAATTGCTGGTTCCTGCGCCCCACCCAATCTGCGGTCACTG GGACAGGGGTCTTGCATTTTAAGGAGCACCCCACCGCACCCCCATTATTTTCCAAGTACA CCAAAGTTTAGGAAGCGCAGGCCTAGGGTAGCGAACTGTCATCGTACGTGGCCTTACCCC TCCCGGAGGGACCTGGCTTCCTCCCTGGGTGTGAGTAGCGCCAGCTACTAGGTCCAACGG GAGCCTTTCTGTTGCGGGGCTTCTGCTGAGCGGGTGGGGGGGGTGTGGGCGAGTAGTGTG AGGCGCCTTGGGAGGGGAGTTTTGGGCCAAGCAGAGAAACGATGAGGGTCAGATGAGTCC ACTGAGGCCCTTCGCCTGGTTGGTTGGGGCTGACCCTTAGATTCTGGGGCCACGGCGGCA GGACTGAGCTTCATCTTTTTGCCTAGGCCAGGAACGTCACTGGGGCGTATACGGAAAGCA GGTCTGGCCTTGTTTTTCGCCCTGGGAGATGGGGTGCAGGGAGCAGCAGGAGGGCCGCCT GTGGTGGGGTTGTGGGTGCACTGAGGTATACTTTGAGTGTGAGACCTTTGCATTTCCAAG AGCCATCAGTTATTCAGGGTTTGGGAAAGGGATAGGCCTTCGAGAGTTGTCTGGCCTGGG GAATGGATTTTCCTTTTTAAAATGCCATTTCTCTTCCTTTCCTGGGTGTATGCTGAGGCT CCCATCCCTGTGGCTGTCACTGTTGAGTTATAAATAGCTTCAGCACATCAGGTGAGGCCA GCCTCTCTCCTCCTGCTTTGGGACCTCATGTGCACAAACCCTTTTGTTTGTTTTTGAGAC GGTGCTTTGTTCCAAATCTGGGGCTGAGACAAGCTGCAGGGACAGGTGTACACATCTGAC AGTTTCTTGTTTGAAATTACCAGGTAATAACCATCCATAACAAGAATTCTACCCGATATT CGTAGAGTGCTCGCAAAGCACGCTGACATCATCTTATTTCATTAACAGTCCTAGAGGGTA TTCTCCCCTCTTCCCAGATGAGGAAAATTGAGGCTCAGGGAGGTGAGGGTGCTTCCTCAA GGTCACACAGCTATAACTTTTGACCCTCAGTTTGGTGCTCTTTCTACTGTATCATGCTGG CAGCCACTGTTGCATGACCTGAGTGATGGACTAGTCCTTTATCTCTTACAATTTAAAATT CCACCTTACAAAAACACTGATTTAAAGTATCCTTTATTGCTTAGGCCAGGCAAAACCTGG AACTTATTGTTGCCTGTCTTTCACTATGGCTGCTTTTCTATCTCCTGCCTTCTCCTGCCT CCTTTGATCCCAAATGACCCCACCCGACATGGGTCACAGTCATTTCTGAACAGAGTGAGG AGTCCAGATCTCAAGGGAGGAGAGCAGGAAGGCCATCTGGCCCACCCAGCCCACCAAGGC TTGACTTTCTTACTTCTCAGTTGGTTTTAAACCAAAGCCTGGTATAGAAAGCAGTTGCAG GAATTCAGATTAATTTGTATTAGAAAGCCATGACCAAGTTGTTTGTCAAAACCTCCACCT TCTTAACTCACTGGGTGTGTTCATTTTTATTGGACCAACAAGCTGCTATTTGGTCTGGGA GTCCATGTGTGGCTGGTTTATTTCCAACTTAATCATATTTGATTTCTCCTTTTCACTTAT AAATCCAGAGTTCAAAATTGTCTCCCTCAATTTTGAAAACCCATCATGAGCTTGTCATGA TTTTATCTCCCACTTCCCTGATTAGCCTCCCTGTCACTTTGATTTCCTTCCAACCTTGTC ACATTGCTCTCTTCTCTTTTTTTAATTGCCCTCTCTTGGATATCCACATGTGTAACTTTG TGACTGAGACAATTGGGTAGATCCAGTCCCCACTAATTGATTAGTTTTCCTTTGAATAGG AGCAGTCTTTCTTCTTCAACTCCACCCCTCTCCTTCCTCCCAGAAAACCTGCCTTCAGTC TTTTCTGCTTATTCAGGAATAAAGGTCTCTTGAAATGGTTGCTCTGAAAAGGGTCCTGAA AAGACAGCTCCAGGCCCTTTCTAATAAACCTAACCTGAATCTGTTTGCAAATCCAATATT CTACAGTTAGTATATATATTTTCCCATAGTCCACCGTCTGCCTACCCCTTGTTGGGCCCT TGAGATCTGGAAATAAATCAGTTCATACTTTCAGTGAGCCCACAGTAACAATGATGCCTA CAGTGTGCCAGGAACACTGTAAAGACACTTTTTTTTTCTTTCGAGACAGACTTTCGCCCT CGTTGTCCAGGCTGGAGTGTAGTGGTACAGTCTCGTCTCATTACAAACCTCCGCCTCCAA GGTTCAAGCAATTCTCCTGCCTCAGCCTCCCAAGTAGCTGGGATTACAGGCATGCACCAC TATTCCTGACTGATTTTTTGTATTTTTAGTAGAGACGGGGTTTCACCATGTTGGTCAGAC TGGTCTCAAACTCCTGACCTCAGGTGATTTGCCCGCCTCGGACTCCCAAAGTGCTAGGAT ACAGGCGTGATCCCACTGCGCATGGCTGTAAAGACACTTTCAAATGTTATCTCTGGCCAG GCCCTGTGGCTTATGCCTGTAATCCCAGCACTTTGGGAGGCCAAGGTGGATGGATCACCT GAGGTCGGGAGTTCAAGACAAGCCTGACCAACATGGAGAAACCCTGTCTCTACTAAAACA AAATTAGCCGGGCATGGTAGCGCATGCCTGTAATCCCAGCTACTTGGGAGGCTGAGGCAG GAGAATCGCTTGAACACGGGAGGCGAAGGTTGTGGTGAGCTGAGACCGCGCCATTGCACT CCAGTCTGGGCAACAAGAGCGAAACTCCTTCTCATAAAAAAAAAAAAGTTATTTCTAATC TTCACCAAAGAAACATCTTTATCCTTATGTACAGTGGAGGATACCAAGGCTCAGAGAGGT TAAGTAACATGGCTAAGGTCACACATCAAACAGCAAGTGGCAAAAATGGGACTCCTCCCT GGGCTGGGTTGCTGTGGAGAAGCATAACTGGAGGGAACAGGACAGGGGAACACAGAAGTT CTTGGCCTGAAGATCTCAGCCCTTTCTAAGCTAAGGTATCAGGAAAGGTCAGAGACTCCA TTTCCCTCCTTGTAGTCTCTCTCCTGCAGATGCTAATCCTACAGCCTATTCTGTTTTTGT TTTTGTTTTTTTGTGACGGAGTTTCACTCTTTGTGGCCCAGACTTGGGGTACAGTGGCAT GATCTTGGCTCACTGCAACCTCTGCCTGTCAGGTTCAAGTGATTCTCCTGTCTCAGCCTC CTGAGTAGCTGGGATTACAGGCGCCCACCACCACACCCAACTAATTTTTGTATTTTTAGT AAAGACAGGGTTTCACCATGTTGGCCAGGCTGGTCTCAAACTCCTGACCTCAGGTGATCC ACCCGCCTCAGCCTCCCAAAGTGCTGGGATTACAGGTGTGAGCCACCGCCCCCGGTACCT GGCTAATTTTTGTATTTTTAGGAGAGACAGGGTTTCATCATGTTGGCCTGGCTGGTCTCA AACTCCTGACCTCGGGATCCACTCGCCTGGGCCTCTCAAAGTACTGGGATTGCAATCCTG ACCCCCCCGCACCTGGCCAGTGCTACAGGCTATTCTGAATTAACCCTGTGGCCAGGTGCA GTGGCTCACGCCTGTAATCCCATCACTTTGGGAGGCCAAGGCAGGTGGATCACCTGAGGT CAGAAGTTCGAAACCAGTCTGGCCAACATGTTGAAACCCCAGTCTCTACTAAATACAAAA AAAATTAATCAGGCGTGGTGCCGCATGCCTATAATCCCAGCTACTTGGGAGGCTGAGGCA GGAGAATCGCTTGAACCAGGGAGGCGGAGGTTGCAGTGAGCCTAGATTGTGCCATTGCAC TCCAGCCTGGGCAACAGAGCGAAGCTCCATCTCAAAAAAAAAAATAAAACAGGCTGGGCG TGGTGGCTCATGCCTGTAATCCCAGTACTTTGGGAGGCTGAGGCGGGTGGATCACCTGAG GTCAGGAGTTTGAGACCAGTCTGGCCAACATGGTGAAACTCCGTCTCTACTAAAAATACA AAAAATTAGCTGGTCATGGTGGCAGGCTCCTGTAATCCCAGTTTACTGGGGAGACTGAGA CAGGAGAATTGCTTGAACCCAGGAGGCAGAGGTTGCAGTGAGCCAAGATTGCGCCATTGT AAGCCAGCCGAAGCAACAAAAGTGAAACTCTGTCTCAAATAAATAAATAAAATAAAATAA AACAGGCCAGGCATAGTGGCTCATGCCTGTAATCCCAGCACTTTGGTGGGTGGATCACCT GAGCTCAGGAGTTCGAGACCAGCCTGGCCAACATAGTAAAACCCCATCTCTACTAAAAAT ACAAAAAATAGCTGGGCATGGTGGTGCGTACCTGTAATCCCAGCTACTCGGGAGTCTGAG GCACAAGAATCGCTTGAACCCAGGAGGTGGAGGTTGCAGCGAGCCGAAATTGGGTCACTG CACTCCAGCCTGGGCGACGAGCAAAATACTGTCTCAAAATAATAAAAACTAAAATAAAAT TAAATAATGAATTAACCCTATGACCGCTTAAGGTCTCAGAGTATGTGGTAAGCCTTCTGG GAAGGCCAGGCATGGATGAGGATGGGATGCCGTGTCTAAAGGAAAACAGCCGGCCTGGTT CAAGTGCGAGATTCGAACTGGAGAATAGAGTAGGTTCTTGAAATGCATGGGTTGGAATCG GGGCTCTGAGAAAGATGGGCCAGGCCTGTGAGGCTCACTGCCCACTTCCTGGGATTGAGT TACTCTCCTGTGTGGTATTTCATCGCAGATTTTGTTTCTGCAGATAAGGAAAAGGGGAAG GAAAAGCTGGAGGAGGACGAGGCCGCAGCCGCCAGCACCATGGCTGTCTCAGCCTCCCTC ATGCCACCCATCTGGGACAAGACCATCCCATATGATGGCGAATCTTTCCACCTGGAGTAC ATGGACCTGGATGAGTTCCTGCTGGAGAATGGCATCCCCGCCAGCCCCACCCACCTGGCC CACAACCTGCTGCTGCCTGTAGCAGAGCTAGAAGGGAAGGAGTCTGCCAGCTCTTCCACA GCATCCCCACCATCCTCCTCCACTGCCATCTTTCAGCCCTCTGAAACCGTGTCCAGCACA GGTTGGTGAAAGGCCATCGAGGAGGGCCACCTGTCCCATCCAGGGAAGTCCATTTCCCAC TGAGGGCTGCTTGTGTCCATGTACCCAGTGAGTCCCTTCTCTGAGGGGAGGTCCTGGTGG GGCTGCAGTGTGGAGAAACTCTTCACTCCCCACCCTTCCACACAGTTCCCCGAGGCTGGA GATAAAAATAGTGGTCATGTCACTGGCAGTTGGAACCCTTCTGTTGGTTGCTGTGCTGCA AACAGTCAGGACAGGACCTTCCAGGCCACGGCATTACAGGATAGAAATCCCATTCTGCAT TTCCTCAATGCTGCTCTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTGAGAAGGAGTCT CGCTCTGTTGCCCAGGCTGGAGTGCAGTGGAGCAATCTCGGCTCACTGCCACCTCCACCT CCTGGGTTCAATCAATTCTCTGCCTCAGCCTCCTGAGTAGCTGGGATTACAGGCACCAGC CACCACGCCTGGCTAATTTTTTTATTTTTTAGTAGAGACAGAGTTTCATCATGTTGGCCA GGCTGGTCTCGAACTCCTAACCTCTGGTGATCTGCCCGCCTCAGCCTCCCAAAGTGCTGG GATTACAGGCGTAAGCTACCACGCACAGCCTTAATTTTTGTATTTTTAGTAGAGACGGGG TTTTGCCATATTTGTCAGGCTGGTCTTGGCTCACTGCAACCTCCATCTCCCGGATTGAAG CGATTTTTATTTTTAGTAGAGATGGGGTTTTGCCATATTTGTCAGGCTGGTCTTGAACTC CTGACCTCAGGTGATCGACCTACGTTGGCCTCCCAAAGTGGGGAATGCTTTCTTTGTGCC AGGGCATAAGCACTATTCAAGTGCTACCTCCATTACCTACTAGCCTGGGCAACAGAGTGA GACGCCATCTCAAAAAAAAAAAAAAAAGAAAGCATTCCCACCACCTGGCCAGGACAAACA TCATCTTCAGAGTCTGTCCTTATTCCTCCTCCTTTTACATTTTATCTCTGGGGGTTTGTT TTCATGCTCCTTGGACACGAACCTACCAAAGGAGACATGGCTCCTGTTGCAGGGGTTCTG CAAAGCTTTCTGCAGTCTCTGAGGCATACAGGCTGATAGCTCCTGCCAGTCGGTATGTCA CCCCAGGAATCCACACCCAATAAGTTCTCATACTCTATTTTTTTTTCTTTTTATTGTGGA AATTTTTTCAAACAAAATACAAAAGTAAGAGACGACTATAATGAACCTCTATGTAACCGT CACCCAGCTTCAACAATTCTCAACTCAGAAGCAGTTATTTTCAATCAAATTATAAGTATT TCAATATGTATCTAAAATATAAGGGTTCTTTTAAAAAAAACATAACGAAAATACTAGTTT TACATCTAAAGTTGACAATAAATCCATCAACATTCAGATTTCCAAAGTTGTCTCATAAAT GGTATTTTACAGGCCGGGCGCAGTGGCTCACGTCTGTAATCCCAGCACTTTGGGAGGCCG AGGTGGGTGGATCACGAGGTCAGGAGATTGAGACCATCCTGGTTAACACGGTGAAACCCC ATCTCTACTAAAAAGTACAAAAAATTAGCCGGGTGTGGTGGCGGGTGCCTATAGTGCCAA CTACTCGGGAGGCTGAGGCAGGAGAATGGCGTGAACCCAGGAGGCAGAGCTTGCAGTGAA CCGAGATTGCACCACTGCACTCCAGCCTGGGCGACAGAGCAAGACTCCATCTCAAAGAAA AAAAAAGATCGAGACCATCCTGGCCAACATGGTGAAACCTCGACTCTACTAAAAATACAA AAATTAGCTGGGCATGGTGGTGCGTGTCTGTAATCCCAGCTACTTGGAGGCTGAGGCAGG AAAATCGCTTGAACCCGGGAGGCGGAGGTTGCAGTGAGCCGAGATGGCGCCACTGCACTC CAGCCTGGTGACAGAGCAAGACTCCATCTCAAAATAAATAAATAAAAGTTTTTTTTTTTT TTCTGTAGAGTCAGGGTATCACTGTGTTGCCCTGGCTGGTTTCAAATTCATGGCCTCAAA CAGTCCTCCCACCTGGGCCTCCCGAAGTGTTGGTTGAAATTACAGGCATGAGCCACTACA CCCAGCCGCTTTGTTAAGTTTCATTGCTGAATAGTAGTCAATTGTACTAACGTACCACAG CTTATCCATTTAACCGTTGAAGGACATTCTGATTTTGGTTATGAATAATGCTGCCATGAA CATTCATGTGCATGTCTTTTTTTTTTTTTGAGACGGAGTCTTGCTTTTGTCGCCCAGGCT GGAGTGCAGTGGCGGGGTCTCAGCTCACTGCAACCTCCGCCTCCTGGGTTTAAGCGATTC TCCTGCCTCAGCCTCCCAGGTAGCTGGTATTACAGGTGTGCGCCACCACTCCTGGCTTAT TTTTGTAGAGATGGGGTTTTGCCATGTTGGCCAGGTTGGTCTCAAACTCCTGACCTCAGG TGATCCACCTGCCTCACCTTCCAAAGTTCTGGGATTACAAGTGTGAGCCACTGTGCCTGG CCCATCTACATGTTTTTTGGTAAATATATATATGCGTTTCTTTTGGGCATTTGCTTAGGA AGAGAATGGCTAGGTCATTGGACATGCATATGTTCAGTTTGTGTAGACCCTGCCAAATAG CGTACAAAGTTGTTATATCCATTTGTACTCACACCAGCAGGGCATTGGAGTTCCATTGTC AGCCTTTGATTTTGACATCTTTTGTAATGGTGGACCTATGAGAGAATTATATTTCAGGCA AGTTACCAACAGATCTATTCCCTTTCCCTCTTCTTCCAGCAAAGTCATTTTAAGGTCTCA TTGTCATCTTTTTTTTTTTTTTTTTTTTTTTTTGAGATGGAGTCTCACTCTGTCACCCAG ACTGGAGTGCAGTGGTGCGATCTCGGCTCCCGCAACCTCCGCCTCGCAGGTTCAAGTTCT CCTGCCTCAGCCTCCTGAGTAGCTGGGAATACAGGCGCCCACCACCACACCTGGCTAATT TTTGTATTTTCAGTAGAGACAGGGTTTCACCGTGTTGGCCAGGCTGGTCTTGAACTCCTC ACCTCAGGTGATCCACCTGCCTCGGAAAGTGCTGGGATTACAGGCGTGAGCCACTGCGCT CAGCCCTCATTGTCATTTTCTAGAATTTGTTCATAGAGGTATCCATGGGGAAATGAGAAT TCCTCAAAATCTTGTCCCCAGGCCTCTTTGCAAATTTTCCCCTTTTGTTTCCTGCGGCTT TCTCTTATCCTGTCCCTGAAACTTAACCACATCTTGCCACTTGGTTGTTGCTGAAGGGCA CCCAGGCATGGCGTCACTTTGAACAACATTCTCATGTGGTAGGTACCTGAGCTGCTTGTC TTGCAGGTACTAGGTTTGGCATGCCCGAAACTGCCTACAGTTACCATGTGGGTCCCTGGT CATTCACTCCTCTGACACTCAGATGTCTCTGTAATTAACCCCTGTCTAATAGGATACAAT GAATTTATGTGCATAATCCAATTAAAGCCTAAGTCTGATCATGCCACACCTCTGCCCAGA GCCCTCCAGGTGTTCTATCTCAGGATAAAAGTCAGAATCAGCAGCACCATTGACATTTAG ACCAGATGATTTTTTGTTGGGGTTGGAGGCGTGACTGACCTATGCATTGCAGGATCTTCT TTTCTTTTTTTTTTTTTTAAGACAGTCTTATTCTGTCACCCAGGCTGGAGTGCAGTGGTG TGATCTCAGCTCGCTGCGACCTCTGCCTCCCGGGTTCAAGCGAGTCTCCTGCCTCAGCCC CCTGAGTAGCTGGGATAACAGGCACGGCCGGCTACTTTTTGTATTTTTAGTAGAGACGGG GTTTCATCGTATTGGTCAGGCTGGTCTCGAACTCCTGACCTCAGGTGATCCACCCACCTC AGCCTCTCAAAGTGCCGGGATTACAGGCATGAGCCACCACACCAGGCCGGCATCTGACTT TTTTTTTTTTTTTTGAGAGGGAGTCTCACTCTGTCGCCAGGCTGGAGTGCAGTGGCACCA TCTTGGCTCACTGCAATCTCTGCCTACTGGGTTTAAGCAATTCTCCTGCCTCAGTCTCCT GAGTAGCTGGGACTACAGGCGCATGCCATCACGCCCAGCTAATTTTCGTATTTTTAGTAG AGACGGGGTTTCACCATGTTGGCCAGGATGGTCTCGATCTCTTGACCTCGTGATCCACAC GCCTCGGCCTCCCAGAGTGCTGAGATTACAGGTGTGCACCACCACGCCTGGCCCATCTGA CATTTTTATATATCGTTTGTATTTATCTTGTGTAATGCAGCTTTCCCCACTAGAATAACA TTTCATGCAGGCAGGGATTTTTAGCTGTTTGTTAACTGTTTTGTCTTTGCCAGGACAGAA CCTGGCATATAACAGGTATTCAATAAGTATCTGTTGACTGAATAATTATTTTGTATACTC CTATCAGTAGCATTGAATGAGCTGGCCAAAGGTATAGTTTTTCTTAATATAACTCTTATC TCTAATAACACACAACCTTAGAATTCTAGAGGTGGTTTTAACCCAATCGGTGTCCACTAT TAAATGGCAGCCAGGTGGGGCAGGGAAGAACAAGGAATCAGCCAGCCAGACTAAGTTTCA AATTTTAGTTCAATTGCTTATCATCTGTGTGACTCTGGGAAAACCATTTTATTTCTCTGA GCGTTAGTTTCTTCATCTGTAAACTAGTTGTCATAAGACTAAATGGGGCCGGGCGCAGTG GCTCACACCTGTAATCCCAGCACTTTGGGAGGCCGAGGCAGGTGGATCACCAAGTCAGGA GATTGAGACCATCCTGGCCAACATAGTGAAACCCCGTCTCTACTAAAAATACAAAAATTA GCCGAGCATGGTAGTGGGCGCCAGTAGTCCCAGCTACTTGGGAGGCTGAGGCAGGAGAAT AGCTTGAACCCAGGAGGTCAAGGTTGCAGTGAGCTGAGATCACGCCACTACACTCCACCC TGGGAAACAGAGTGAGACTCTTCAAAAAAAAAAAAAAAAAAAAAAAAGACTAAGTGACTA GATGGCACAGTAACAGACATGTCTCAGGGACTCAAAAGTGGAACCCGGGCTGGACGTGGT GGCTCACACCTGTAATCCCAGCATTTTGGGAGGCCGAGGCGGGTGGATCACTTGAGCTCA GCAGTTCAAGACCAGCCTGGCCAACATGGTGAAACCCTGTCTCTACTAAAAATACAAAAA CTAGCCAGGCGTGGTGGCTTATGCCTGTTGTCTCCACTACTCGGGAGGCTGAGTCGGGAA TCGGTTGAACCCGGGAAGTGGAGGCTGCAGTGAGCCAAGATTGCACCAGTGCACTCTACC CTGAGTGACAGAGCAAGACTCAGTCTCAAAAGAAAAAGAAAAGTGGAGCCTGGCCAGGTG CAGTGGCTCACACCTGTAATCCCAGCACTTTCAGAGGCTGAAGCAGGAAGATCACTTGAG CCTAGGAGTTTGAGACCAGCCCTGGCAACATAATGAAACCCTGTCTCTAAAAAATAAAAA AAAATTAGCCAGGCGTGTTGGTGTGCATCCGCGGTCCCAGCTACTCAGGAGGCTGAGGCA AGAGGATCACTCCAGCCCAGAAGGTCGAGGGTGCAGTGAGCCATGATCATACCACTATAC TCCAGCCTAGGTGACAGAGCAAGACCCTGTCTCAAAAAAAAAAAAAAAAAATTGGAACCC ATTTCCATTCTTCAGTCTGTGTCTGCCTGGAGAGACACAGCTGTTTCTCATTACTGGAGA TCTTGAAATCACAGGAAGTTAAGGGAATATAAAAATTTAATGTTTTAGGCTGGGCGCAGT GGCTCATGCCTGTAATCCCAGCACTTTGGGAGGCCAAGGCAGGCGGATCACAAGGTCAGG AGATCAAGACCATCCTGGCTAACACAGTAAAACCTCATCTCTACTAAAAATACAAAAAAA TTAGCCAGGCTTGGTGGCGGGCACCTGCGGTGGCAGGCGCCTGTAGTCCCAGCTACTCAG GAGGCTGAGGCAGGAGAGTGGCATGAACCCGGGAGGCGGAGCTTGCAATGAGCCGAGATT GCGCCACTGCACTCCAGCCTGGGCGACAGAGCAAGACTCCCATCTCAAAAAAAAAAAAAA AAAAAAATTAATGTTTTGCTTAACATTTCTGGAGGGGGTGGAAACAATTGGAAAACCCTG TCTTTTTCTAGGGCTTCTGTTTCCTTTTGAGCATTCTGTTCCTGAAGGAAAGAATTCTTT GAATGTTTGTGTTGTGGAATTGAACCGTGTGCCAGTCTGGCTTAGGGGCTGGTACTGTTG GGGTTTTCTTCTCCCCAGGCGGCAGTGGCTTATGCAGCCTTGAGGTTCAACCAGGTGTCT GGGTGTGTGGCGTGGGTCTTCTCTGTCCAGTGGGCTGCTTCGGGACCACCTGTCTCTGTG TCTTTTAGAATCTTCCCTGGAGAAGGAGAGGGAGACTCCCAGTCCCATCGACCCCAATTG TGTGGAAGTGGATGTGAACTTCAATCCGGACCCCGCCGACCTGGTGCTCTCCAGTGTGCC AGGCGGGGAGCTCTTCAACCCTCGGAAGCACAAGTTTGCTGAGGAGGACCTGAAGCCCCA GCCTATGATCAAAAAGGCCAAGAAGGTCTTTGTCCCCGACGAGCAGAAGGTAACCTGGTA TTCCTTATAAATAAAGATGCAGCGTTGGTTCAAGGGCCTAGGGGATATGGCTCCTCGCAT TTGATTTTATCTGGAGAGCCTTCCCTCCTTGTGACACCATTTGGAAAGACATGAGTTTAG TGCTTAAAGCCATATCCTTCAGCAGTTTGGTAGAAAGAAAGGGAGTCATGTGGCATTTGG CCCCAGTGTGACTCCCTGTAGTTTCTCTCCTTCCCCGGGCCATCGGCTGTGTTGATGTTC CTGCCTCCCTGGCTGTAGCCCAGCCACTGGGCAAGAGCTCACTAGGCCACAGGAACTGGG GTTGAAAAAGTCCTTGCTTTGAAGGACAAAGGGTTTCTTGTATGTTGCCATCCCCAGGGA TGAGCAAGCAGCTTTCAAGCTGGTGGTGCTGTTAGGAACTGGTGGGAAGAGAGAATTTTG CAGTTTTCCATCCTTTCCTATGAAAAACTTACAGCAAGGATTTTTCATCCAAATCTTTGG AGTCAGGCACACCTGGGTCCAAACTCCATGTTGCCACTTGTGGCCTAGCTGTGCCTCAAG TTCCTCATCTGTAAAACGGGAGCAACTGAACCTCCCTCCCGGGGAGGTTTGTGAGACTTT AATAATGATGTGATGATCATGGTGAATATTTAGATGGTACTCACTGTAGGCCAGGCACTG ATTTTTGTTTTGTTTGTTTTTGTTTTGTTTTGTTTTTGAGACAGAGTCTCACTTTGTCAC CCAGGCTGGAGTGCAGTGGCGTGATCTCGGCTCACTGCAACTTCCGCCTCCCAGGTTCAA CCGATTCTTGTGCCTCACCCTCCTGAGTAGCTGAGATTACAGATGTGCACCACCACGCCG GCTAATTTTTGTATTCTTAGTAGAGATGGGGTTTCATCATATTGGCCAGGCTGGTCTTAA ACTCCTCACCTCAAGTGATCCACCTGCCTCAGCCTCCCAAAATGCTGGGATTACAGGTGT GAGCCACCATGCCTGGCCTGTTATTTCTCAGTGTAAAGATAAGGGACCTGTGATATTGAG GGGTTAAAGTACTTGCACAGTTTCACTGCTAGTAATCTTGGAGAGCCAAGATCTGAACTC GGGGATCTAGGCCCTTACCCACAACCAACATGCCTAAGTAAGGCAAGGGTGTGGACAGTG CAATGCTTTGTGCTGGAGCAGCAGGTACCAGGCCTCCAGGAGATGAGTCTCCTTCTCTTC ACCATGTAACGTACCAAATAACTTTTGTTTCTCGTCCTGCCCCCGAGGAAAGGGCAGTGC CCTCAATGTGCCCTGGTTTGTGCTGCTCCCTCCCTGGTATCCCTGCTTTAGCTCTGGCCA CACCAGATGAGTTAGGGGAATCCAGGTGGTGGGAGTGGAAAAATTGGGTTCTCTCGTGGG GAAAGACGAGAGACTCACAGAGGGCACTTCCCCACAGGATGAAAAGTACTGGACAAGACG CAAGAAGAACAACGTGGCAGCTAAACGGTCACGGGATGCCCGGCGCCTGAAAGAGAATCA GATCACCATCCGGGCAGCCTTCCTGGAGAAGGAGAACACAGCCCTGCGGACGGAGGTGGC CGAGCTACGCAAGGAGGTGGGCAAGTGCAAGACCATCGTGTCCAAGTATGAGACCAAATA CGGGCCCTTGTAACCCGTGCCCCCCGCCCGGGCGGGGTACTGCCTGCACCTCAGACCTCT GCCTGGGGGCTCCCTGTAACCCCTCACACGCGTGGAGACTTATGACTCGTCGTGGGCGCA TGGCGGCGCACCTGCTGCAGGAGCGGCCACGTCTCAGCTTCATTATACCATGGCCTGCGC ACGTGGCGACGTCCCTGAGGGGCCAGTCTCCTCACTGGTGGGGAACGCAAGAGAATCTGC GTAGATGGGTGACTCAGCCTTAGTTTCTATTCTTGGATGTCCCAGTTGAATCAGAAGGGG ACCTCTGGAGTACACACCTCTCTCCTGGGCGCTCAGGGTCCCTGGACTCTCCCTCAGTCT CCAGCCTGGGCTGCCGAGGGCTATCTCTGCAGAATGAGTTGTGATCATTGTCACCCTATG TCTTCTCAGGTAGCAGGGCGCGTTTCCACTTAAGGTGTGTCTGTCACGCACCTCATTCTC CCCAGACAGTCTTTGAGTAACATCTGTTCCCATCTTCCTTGGAAGCAGGACACACCAGCT CCTCCGTCAGTGTCTGCATGGGTAGCAGGCTGCAGGAGTGGGGTCTCTGCACAGCCTGGG ATGGGGCTTGGGGCTGGGGCCTGCAGCAGAAGTGTGCCCAGCGTTTCTCGGCTCCCGCAC CCCTTTTCCCTTATGGCTCTGAGGCCATCGGCTGTCTCTGCATTTCATTGGCTGTGGAGG AGAGACTCCTAGGATGGCTGCTGTCTGAGCCATGAGTGCCAGGGCTGAGAGAGGCCTCTT CATTTCCTCTCCAGGCTACTCAGAGGCCATGTGAAGCTCGTTTGTCCCACTAGACCAGGC CTCTGGGCCTGCTCTTTCTTTCCACCCAATGTCCAGTCTTGGATCATAGATTTAAAAGGA AAACCCCTCTTATCTAGGAGGCTTTAACTTCCTGGACCCCAGGATTCACCTTCCTAGTGG TGTTTAGAAAATGCCTCCACAGCCCCCTTCCACCATGGGCATGAGAGCTGGGGTGTGTTT CTTGAGAAGCTCCCTTTTTTCTTGCTCTGCTCACCGGTGTGGCCTGGGCTGGAGTGCACT CTCCCTGGGGGCAGCTGGGGCCTCGCAATTCTTGCTTCAGGATCTCTCCCATGCGAGCTG CCCGGAGGGTGTCAGCAGGGCAAGACACCTAGTCTAGAGTCACCAAGGTCACAGTGCCAC TTTCACGGGATAGCAGGCTCTTGGGACTTTTACACAGGCCTAGGGTCCCCTCAGTCTTGG TCCCAGGAGATGGGGGCCACTCGTGAGGCTGGCCATGCTGTGGCTTCTCACAGCTGTGGT CTCCCCTGCCTCACAACGACTCCTTTCTCTTGTGTGGCGGGACTCGCCCTTTTGCTGTGC TCAGAAGATTCACTGAGGAAACTCATGGAAGCCTCTGCTCATTTGGGTCACTGGGACACC CCTGAGATGGGTGTGTTTATTTGCTCAGGGCGGGCAGCCTATGGTGAAGAGGAGACAGAG GCGATGGGCGTGCTTCGTCCTCCGTAACACTGGCTTTATTTACCGTGGTGGTTCAGAGTC CCAGGCCCTGACCTCTAAAGACTTTTCATAACAGACGTTAAGACCAAGCCGTGGACCTCA CCCCAGGGGAATGCCACGGCCCTTTGGGGACCTGCACACCCACCTCTCCGGGGGACTTGA CAAGGGGCCCTGAGGCCAAGGGAGGTCACTCCTCCCTCCAGGCCCCTGACTTTTACTTTG TGGTTCTCTAAAAACCATGTACACACTTTCACTCTATTGTAACCACACAGGGCAGGCGCA TCCAGCATGTCAGTGTCCTGCCCCGGGCAGCTCTCCCTCCCGGGCACGCTCCCTCTGGCC TGGTGGATCACCAAGAGGGCGGTTCTCATTTTGTTATTAGTGGAAGAGCCTTGAGCTTAA AAGCTCTTCATTTTCTTTGCCGGAAAGTATATGGTTTGTGTTTTTGCAGTTTTATTTTTT TAAGGATGGACACTAAATCTCTGGTGTCCATGTTCCGAGCCCGGTGGCTGGGATGGTGGC TCGATGTGTCTCCTCTTTATCCCGCCCTCTGCCTGTTTGGTGCCCTCCCTTCTTTCCCCC AGGCAGTGGGTATCGGGTTCTTTCCCAAAGTGCTTACTTGGAAAGAGTGTGGCTGCTGGA CTCTTTTCGAAATGCCCCTCTGAGTCAGGAGCCTGGTGGGGACAAGATGGAGGATGTCCA CAGAGGCTGACCTGTGGGGGAAAAGAAGTGCTCAGGTAAGGTTGTCTCCTCTCCTGTCCT AAAAAAATCCATGCTTGCAGGAGAGGGTTGGTGCCTGCTCAGTTTCTGTCGAGGGAATGG GAGTCTCCTCGGCTCCCTCCTGGGCCCTCTGCTTCTTGGAGGCCGACCGCTGGAGACTGC GGCTCCTGTGCTTGGATCTTTGACATCTGTCAGTCACTGGAGGCTAGAGAAGTTGACTTT ACCTTGGCTTTCTGTGGGTTCCCGATGGGCTTGGAAGTGCCGTCTACTTCCTAAGCATCC TGTCTAAAGCTTTGTGGCACCCTCAGTGCAACCTCAGAACAGACAAATCATGAATGAGCT GGAACTTTGCAAGAATATTCATATTATAAATGTCTCATCTGATGGAGGAACGTGTGCATT TAGAGAGAGGGAGAGTTTTCAAGGTTTATGGCAACTTTGTGGAGGACCTGGGTAACTCTT ACCCTTGGCCAAAGGAAGAGGTTTTCCTGTCTGGCTTCTGAGGTTGGAGGGGGCACTTAG CAGTGAACCTTAAGTCTGGGTACATGTAACCCTGCTGAGGGGCTGTGCAGGCCGCTCCTA CGGTCCTTTGGCCTGAGGCAGGGCGGGAGGCATGCAAGCCAGTGGGGGAAAACCCCTCTG AAGCTGGGCAGCCCTCTACCTGGGCCCCGGGAGCCGTGCTCCTTGGAACGCAAAGGGCCG AGGAGCATCTGGTTTTCATGGCAAAGCTCTACTCCAGAGCTCCTTTAACATCTGCTAATT AAGTGCAATAAATTTTTCTAGAAAATGGCAAAGATGACTTCCAGGTGGATATTGCTCTCT TACGGTGTTGGGGATGCCAGAACACCACTTGGTTTTATTTTTCTAAGTGCATGTGATGTG ATAGAGTGTGTGGGGCTCTGTGTCCTTCCCTGGGAGCTGGCATTCCAGCGGGCCCCTCTC TTTACCTTTGTTGGGGGAAGGAGGCAAGAGAGAAATTCCTTCTTCCCAGCCAGAGAGGGC AGAAGCAGACCGTAGCCCATTGGCCTTATGTGCGTGTGTGCGTGCGAGTGTGTCACTGCT GGTGGGCCGGAGTGATGTGGTGGGAGGGAAGCCGGGAATGTATCCTTTTCAGACAAAATT AAATATTTTGAAATGAGAA OMIM ID 188595