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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for BUB1B (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID701
Official gene symbolBUB1B
Full namebudding uninhibited by benzimidazoles 1 homolog beta (yeast)
Aliases,BUB1beta,BUBR1,Bub1A,MAD3L,SSK1,hBUBR1,
Gene summaryThis gene encodes a kinase involved in spindle checkpoint function. The protein has been localized to the kinetochore and plays a role in the inhibition of the anaphase-promoting complex/cyclosome (APC/C), delaying the onset of anaphase and ensuring proper chromosome segregation. Impaired spindle checkpoint function has been found in many forms of cancer. [provided by RefSeq]
LocationChromosome: 15   Locus: 15q15
Gene position40453210 - 40513337  Map Viewer
Gene orientationplus
Gene size60128 bp
Gene sequence
OMIM ID602860