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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for TFF1 (Homo sapiens) (Information is obtained from NCBI Gene database)

Entrez gene ID 7031 Official gene symbol TFF1 Full name trefoil factor 1 Aliases ,BCEI,D21S21,HP1.A,HPS2,pNR-2,pS2, Gene summary Members of the trefoil family are characterized by having at least one copy of the trefoil motif, a 40-amino acid domain that contains three conserved disulfides. They are stable secretory proteins expressed in gastrointestinal mucosa. Their functions are not defined, but they may protect the mucosa from insults, stabilize the mucus layer, and affect healing of the epithelium. This gene, which is expressed in the gastric mucosa, has also been studied because of its expression in human tumors. This gene and two other related trefoil family member genes are found in a cluster on chromosome 21. [provided by RefSeq] Location Chromosome: 21   Locus: 21q22.3 Gene position 43786644 - 43782391  Map Viewer Gene orientation minus Gene size 4254 bp Gene sequence >TFF1:complement(776832..781085):Length=4254 ATCCCTGACTCGGGGTCGCCTTTGGAGCAGAGAGGAGGCAATGGCCACCATGGAGAACAA GGTGATCTGCGCCCTGGTCCTGGTGTCCATGCTGGCCCTCGGCACCCTGGCCGAGGCCCA GACAGGTAAGGCGTGCTTCTTCCTGCTCTGTGGGGCCACAGCCAGCTCTGGCAGCCTCCG CCAGGAGCCACTGTTTTACATACATATTTTTGAGCACCTGTTTTGTGCCAGGTGCTGTTC TAGGCCCTTAAAAGTATATCCAATTTACAGGATCGGCAAAAGCAGGTGGAGAGTAACTCA GGGTGGCAGGGCCCCCGGAGACCTTCGAGAAGTGCGACGAGGAGGGGGCTGCCTTCAGTC GGGGCTGTTTTCCTGTGTTAGGAAGACTATACAATCCTCCCAAGTGTCATGTTTCAAAGA GGAAGTGTTGGCGTGGGGTCTCAGAATAGTGCTTTTGACTGTTCATGCCAACATCTCCCC CAGGGGCAGACCCTCCCAAGGCCCATCCAGATAGGCCCAAATGCCGGTCCCAGTGATGGC CACCTGGGAGACCCTCTCCCACAGGCCCGAATGCCCGTCCCAGTGGTGGCCAACTGGGAG ACCCTCTCCTACAGGTTCCTGGGCTCCCCTGGGATCCATGCTCTGGGAGTCAAAGCCACC TCTCTCATGAGTGCGTGGCTGGCAACCCATATTCCCTGGTGTTGTCAAGTGGATCGGTTG CCCTGGGTCCTTCTAGGGAGTGGAGGAGGAGGCCATTCTTGCTTCCTTGGGAAGTGTTTG CATCTCAACTCCTTTACCTGCAGAATGGATCAACGGTCTGCCCTAGGGCTGTCAGGAAAT GCTGTGTGGCAGCATCTGCGACTTGCACTTTGCCAGCTGTGGGGAGCTGAATAACTTATT TGCCGTTATTAGGTACAGTTTCAAGGTGGGGGCAGGAGAAAGGGCTTTCTACGTTTCCAA AGCAAGGGTTTCCAGAGAGGCCTGAAGAGGGAGCGCCCAGTGGTGCTGTCCGTGCCCCCA CTGCCCTCCAGCCACCTCTTGATCTCTGCTGTGGGGTACCGGGCCTGAGGGGTGGGCTTG GGCAGCGTAGAAGAGCAGCCAGCATTGGGCTGCAGTGGGAAGACCCCCAAGCCCATGGCA GGGAGCGGGGGAGCTTTGGAACCCGAGAGAGGAAGTGGCCTCGGTGTACAGAACGAACTG GGTGGGTCCCCGTGCTGGCCACCCCCAGGCCCATCTGCCTGCGCCCTTGCCCCCACCCCA GCCCCCAGCTCTGCCCCCTGTGCTGTGGGATCACAGAGGCCGTGGCAAACTCCCCTCCCC ACCCCACACACCCTCTGGCTCAAGGCTCAGAGCGTCTTTGCGGGTCACTCAGGTCCATGA TCCTGTTACAACTGAAATCTAGAAAATTGTGATTACAGTTTAGTGCATTCGTGTGTGGAA ACCATTTCCATTTATTTCCATCATGCGACAAAGACAAAGCGGGTGGGCAAGACAGAGTCT GCCGGAGGCAGAGCACCGGGGCTGGAAATCTTCCTCCCTGAGGAGGAAACCCCCCCGACC CCCAGGATGATGATCCTCCCTCACCACGGGGCCTCTCTTGACCCCCACAGTGTCCCGGGG GTGGGCGATGATCACCTTCACGTCGCGATGGATCCAGACCCCAGGAGGGCAAGGTTCCCA TGGAAGCTGCTGGGCAGCGGGAGCTGAACACGGATCCTTCCCAGCAAGCCAGGAACACTT TCTCCAAAGACATCTCGAGGCAGTCCCTGATAGCAAAGCAGACAAGAGAACAGCCCCTCT CGGCCTCCCCTGGGGCGCCCTCACCTGAGCCAGTGTGGCCAGACTGAGTTCCTCCCCTCC TATGCCCCAAGGCAGGGACAGGGACCGGAGGGTGCTCTGGGCTCCTCTTTCACCCCCTGC TGCAGGCTGTCAACCACCAGATCCTAATAGGTTGCTTTCTGAGACCTTTGATTCCGCGGA GCTCAGAGCCTGAAGCTCTGGTGTTAGAACCTCTTGCATAAGATCCTGCGGCAGCCCCCA GCCAGCCCCATCTGTCCACGTGTCTTCCTCCTCTAGATCCCTTTCCTCACTGCCCTGCTT CAAGCTGTTTCACAGCTTGTACCCTCTGTCGGCTCCTCCTAGACCACCCCACCCGGTCCT CTCACCTTACCTGCAATGGGTTTCCACCTCCTGAACACACCTGGGTCTCTGGAATGGCCT TTGCCCATGCGGCTCCATCTTCACCTGGTGAACCTCCTCCTGCAGGGAGCCCCCCTGCTT TGTTCAACCTGCTTGTCATTGGCCTCTCCGGGGAGTGCCCTACCCCCGTGGTTACCCTGG GCACCCTGGGACGATGGCCTTGCGTTGTCTCGCACATGTTCTTGCCTTTCTCCTCCATCA GATCCTTAGACTCTTTTTTTTTTTTTTTTGAGATGGAGTCTTGCTCTGTCACTCAGGCTG GAGTGCAATGGTGCGATCTTGGCTCACTACAACCTCTGCCTCCTGGGTTCAAGTGATTCT CCTGCCTCAGCCTCCCAAGTAGCTGGGATTACAGACGTGTGCCACAATGCCCGCCTAATT TTTTGTATTTTTAGTAGAGATGGGGCTTCACCATTTTGGTCAGGCTGGTCTTGAACTCCT GACCTCAAGTGATTCACCTCCTTCAGCCTCCCAAAGTGCTGGGATTACAGGCATGAGCCT GGGCCCAGATATTTAGACTCTTATTAATGACTTCTCTGGTTTTAATTTCTGGGTCTCTCT CACCTGGCACAGTGCCTGGCTTTTGCCATGCTAGCTCCCACTTCTCATGCACACAAATGG TGCTCAGTAAATATTTATGTATTGAGTAAAATTTAATAATCATTTGTTGAAATTAAAAAG TGAATAAATAAGTTACCTAGAAAGATGCAAAGTCCACAAACCTGGGGCACCTTGCATTTT CCCTGAGCGTAATGTTTGCACATCAGGATGTGAGGACCACGTCTCCCTCTCATGTCCTGA GGGTTTTATATCCGCCTCACTGGACAGTTGCTGATGTCATTGGAGAAGGAAGCTGGATGG GTGTGTGCATGATAACATCAAGGAATTCAGCCCACAACTTACTTTGCTTCTTACCTGTGC ACTTTCAGAGACGTGTACAGTGGCCCCCCGTGAAAGACAGAATTGTGGTTTTCCTGGTGT CACGCCCTCCCAGTGTGCAAATAAGGGCTGCTGTTTCGACGACACCGTTCGTGGGGTCCC CTGGTGCTTCTATCCTAATACCATCGACGTCCCTCCAGAAGGTATGGCCTTTTTATACGA TGGGTTCTGAAGATTTAGAATTAGTTAGAAAAGTCATTTAAGACTACAGAGGCTCTGATC AGCATCACCAGCTATGCCTTTACACAGAGTCACGGCCGCCAGTGGTGGTGCAATGGGGTA GCCTGAGTCAGGCTGCATTCAGGTCCAGGAATAGAAAGGCAGGGCTAAGGGACTTGGGAA GAAACCTGATTTCCCCCCGGCTTCTCTTCACATCTCTAACCAAAAGCCTGGGAAGAGCCA CTGTTGGTAACGCTTTCTAGCTTGCCTAGGATAGAGGGGGAAGGCATGACGAAATCTGAA GACATTTCATGTATTCTTTTTTTTTTTTTTTTTTTGAAATGGAGTCTCGCTCCGTTGCCC CTGAGCTGGAGTGCAATGGTGCGATCTTGGCTCACTGCAATCTCTGCCTCCTGAGTTCAA CCTCAGCTTCCTAGTAGCTGAGATTACAGGTGTGTGCCACTACGCCCAGCTAAATTTTTT TTGTATTTTTAGTATAGACGGGGTTTCACCATGTTGGCCAGACCGGTCTTGAACTCTTGA CCTCAGGTGATCTGCCCGCCTCAGCCTCCCAGAGAGCTGGGATTACAGGCGTGAGCCACC GTGCCCGGCTGACAGTTCATGTTTTCTAAAGAATGTGCCTATGGATACTTTAAAGTAAAA ACTCTGTAATTGTTTAAATGTGAAAGAAAATGTTTATCCTCACTAAAGCATCTCTTTCTC CCTCCCCCTCACCCCTGTAGAGGAGTGTGAATTTTAGACACTTCTGCAGGGATCTGCCTG CATCCTGACGCGGTGCCGTCCCCAGCACGGTGATTAGTCCCAGAGCTCGGCTGCCACCTC CACCGGACACCTCAGACACGCTTCTGCAGCTGTGCCTCGGCTCACAACACAGATTGACTG CTCTGACTTTGACTACTCAAAATTGGCCTAAAAATTAAAAGAGATCGATATTAA OMIM ID 113710