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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for TFF2 (Homo sapiens) (Information is obtained from NCBI Gene database)

Entrez gene ID 7032 Official gene symbol TFF2 Full name trefoil factor 2 Aliases ,SML1,SP, Gene summary Members of the trefoil family are characterized by having at least one copy of the trefoil motif, a 40-amino acid domain that contains three conserved disulfides. They are stable secretory proteins expressed in gastrointestinal mucosa. Their functions are not defined, but they may protect the mucosa from insults, stabilize the mucus layer and affect healing of the epithelium. The encoded protein inhibits gastric acid secretion. This gene and two other related trefoil family member genes are found in a cluster on chromosome 21. [provided by RefSeq] Location Chromosome: 21   Locus: 21q22.3 Gene position 43771208 - 43766466  Map Viewer Gene orientation minus Gene size 4743 bp Gene sequence >TFF2:complement(760907..765649):Length=4743 CACGGTGGAAGGGCTGGGGCCACGGGGCAGAGAAGAAAGGTTATCTCTGCTTGTTGGACA AACAGAGGGGAGATTATAAAACATACCCGGCAGTGGACACCATGCATTCTGCAAGCCACC CTGGGGTGCAGCTGAGCTAGACATGGGACGGCGAGACGCCCAGCTCCTGGCAGCGCTCCT CGTCCTGGGGCTATGTGCCCTGGCGGGGAGTGAGAAACCCTGTAAGTGAAGGAGAGGGTC TTTTTATGTGCTTTCTTTATTTCTCTTAAAGAAAAAAAAAAAGCACAACCATAAATTAAC TTGAGAGGGGGAATGGCTATAAAGGCATCTGGCAATGTGTGTTGTTCACATGGGATTTGC CACTGCTCAGGAGGGTGGCTCCAAGAAGGGCCTCCCTCCTAGGGAAAGGCTGAGTGACGG CAGGTGTCAGCGGGCCCCGTGTCGGGCCAGGAGGGCATTCCCACCAAGGGTCCTTGGAGT CCCAGAGCACTCACCTCTCGCCTGGATCTTGGCCTTGGGTCCATCTGTTCACCCTCCTCT AGGAGGGTTTTGTTTTTGTTTTTTTCCGAGACAGGATCTGGCTTTGCCGCCCAGGCAGGA GTGCAGTGGTGTGATCTTGGCTCACTGCAACCTCTGCCTCCCAGGCTCAAGTGATCCTCC CACCTCAGCCGCCTGAGTAGCTGAAACCACAGTTGTGGACCATCATGCCCGGCCAATTTT TTTTTTTGTATTGTTTGTAGAGATGGGGTTTCGACATGTTGCCCAGGATGGTCTTGAACT CCTGAGCTCAAGCAATCTGCCCGCCTCGGCTTCCTAAAGTGCTGGGATTATAGGTATGAG CCACCATGCCTGGCTTTTTTTTTTTTTTCCTTTTAAACTAATATAACAATTTCAGCAAAG CCCTATCGGCTTCTCAGGAGGAAACCGCATTGCTTAAATATGGGCAAGATAAGACTTTGT GTTTCTCTATGTGGCAACAAGACAGTAGAGGCATCCCCTAGAACCTCTGAGAGAAGGAGC AGTGTGGTCTGGGGTACCAGGGTGGGGCCGACTGAGGGTCTTTCCACAGCCCCCTGCCAG TGCTCCAGGCTGAGCCCCCATAACAGGACGAACTGCGGCTTCCCTGGAATCACCAGTGAC CAGTGTTTTGACAATGGATGCTGTTTCGACTCCAGTGTCACTGGGGTCCCCTGGTGTTTC CACCCCCTCCCAAAGCAAGGTAATCTTCCAGGGAATCTTCCTGGGCCAGCAGCTGGCAAC CCAGGACCCAGCTTCACAGGCGGAGCCCAGAGCAGGGGCCGGAGGAGGCCCAGTTGCTAG TCTAGGGTTAGCCTGGGTGGGTTAGTCTCGAGCTAGCCCCGGTTGGTTAGTCTGGGGCTA GCCCAGGTTGGTTAGTCTAGAGCTAGCCCAGGTTGGTTAGTCTGGGGCTAGCCCAGGTTG GTTAGTCTGGGGCTAGCCCAGGTTGGTTAGTCTAGGGCTAGTGTAGGCTAGTTAGTCTAA GGCTAGCCCAGGTTGGTTAGTTTGGAGCTAGCGCAGGTTGGTTAGTCTGGGGCTAGTAGC CCAGGTTGGTTAGCCTGGAGCTAGCCCAGGTTGGTTAGTCTAGGGCTAGCGTAGGCTGGT TAGTCTGGGGCTAGCCCAGGTTGGTTAGTCTGGAGCTAGCCCAGGTTGGTTAGTCTGGGG CTAGTAGCCCAGGTTGGTTAGTCTGGGGCTAGCCCAGGTTGGTTAGTCTAGGGCTAGTGT AGGCTAGTTAGTCTAGGGCTAGCCCAGGTTAGTTAGTTTGGAGCTAGCACAGGTTGATTA GTCTGGGGCTAGTAGCCTAGGTTGGTTAGTCTGGAGCTAGCCCAAGTTGGTTAGTCTAGG GCTAGCATAGGCTGGTTAGTCTGGGGCTAGTAGCCTAGGTTTGTTAGTCTGGAGCTAGCC CAGGTTGGTTAGTCTAGGGCTAGCGTAGGCTGGTTAGTCTAGGGCTAGCCCAGGTTGGTT AATCGGAGCTAGCCCAGGTTGGTTAGTCTGGAGCTAGCCCAGGTTGGTTAGTCTGAGGCT AGTAGCCCAGGTTGGTTAGTCTGGGGCTAGCCCAGGTTTGTTAGTCTGGAGCTAGCCCAG GTTGTTTAGTCTGGAGCTAGCCCAGGTTGGTTAGTCTGGGACTAGCCTGGACTGCTAGTC TAGAGGTAGCCTAGAGGACTGCTAGTCTAGAGGTAGTCTAGGGCTAGCCCAGGTTGGTTA GTCTGGGGCTAGCCCATGTTGGTTAGTCTTAGACTAGCCTGGACTGCTAGTCTAGAGGTA GCCCAGGTTGTTTAGTCTGGTACTAGCCTGGACTGTTAGTCTAGAGGTAGCCCAGGTTGG TTAGGTTGGTTAGTCTGGGACTAGTCTGGACTGTTAGTCTAGAGGTAGCCCAGGTTGGTT AGTCTGGGACTAGCCTGGACTGTTAGTCTAGAGGTAGCCCAGATTGGTTAGTCTGGGACT AGTCTGGACTGCTAGTCTAGAGGTAGCCCAGGTTGGTTAGCCTGGGGCCAGCCTGGACTG TTAGTCTAGAGGTAACCCAGGTCAGCCAACAGTGAGATGAAAATTTCCCACCTACCCTGT TTCTACACTGTTAGTTCTTTCAACAGACATGTGTGTGTGGAGCCATCAGTTTTACTTTAG TTGAGAAAAAAATATATATATATATAGTAGGTCTCCTCTAGTTTTTGAAGTGTGACTTCT GAAGAAGCTTCCATGGGGAAATGAAGGTATTTAATAGGACAGCAGTAACATAAGGGCTGA CAGCCCTCAAATGTTAGGGAAGGAAGTGAAGCCTTCTAGGGTTCTTTGGGAGTGAGTTTT ATGTTAGTGCACGGGATCAGGACCCAAGTTGTAACGCCGACGAGTGCTCAAAGGAAGGTT GTGTGTGTGTCGTGCACCTGTGTGCGTGGAACCAGGCACGTCCTCTGGAGAAGGAGGATT CATCCCCAAGATTGTTGCTGGGAGGCTTGCTGGGCCCCGCAGGGAAACCAGGCAGATGGT GGATTGTTCACGAGCGCCCACTGAATGGCAGTGTCTTTGGGAATCAATACCATGTCCAAA CGCTTTCCATCTTACCAAGGTGCCCACAAACCTTTTCTCATCTTGGCCCGGGGGACCACC CCATTTACTGAGAACACTGAGTCCCGAGAGGCAAAATGATTTCCCCAAGGCGGGGGACTC CAGAGCTTCTGACTGTGACCACCCCACATGGGCCCCACCTTCGCGGAGGACAGGCCAGCC AAGCGTCGCTGGGGCCGACACTTCCACAGTCCCCGGGGGAGGCGGTCCCAGGGGCCGACA CTTCCACAGTCCCCGGGGGAGGCCGTCCCGGGGGATGCTGCCCCAGGCAGCACCTCATGA TCCACGGAGGCTGCAAATCAGCGCTGCTCTCAGAGGAGGAAGGGGTGGAGCTTTCCAGGG CACAGCAGGCCTGACTGGGTCTCGGTGCTGTGCCTGTCCCATGGCAGAGTCGGATCAGTG CGTCATGGAGGTCTCAGACCGAAGAAACTGTGGCTACCCGGGCATCAGCCCCGAGGAATG CGCCTCTCGGAAGTGCTGCTTCTCCAACTTCATCTTTGAAGTGCCCTGGTGCTTCTTCCC GAAGTCTGTGGAAGGTAACGTCGCTGTGGGACTCTCTGTCTGGTTCCCGGACACCATGAT TCCTCCTCCGTCCGTAGAGGTGGGGTGCAGGGAGGGGAGCTGCCTCGCAGCCTCAGTGCC ATCGAGGCCAGGGCCCCTGCCTCCTATGGGATTCTGAAGGCAATTCCAGAATGTTCTTGG CAAAGACAGCGTCTTTTCAATAAGTTTATAGCCTCCAGCATTGCCACTGCGTCATCTGTG ATGGCTCTAGAAACAGCGGCTCATCCCTGTTGCCTCCCCAGGTGTTGCAACGTTCAGAGG CGTTGCCTGTTTTATTGCAAGCCCATCTGCATTTGGAGGCTACTGAGTGTCTTGCACTGT GCTGGGTACCAGAGAGGGCCCAACTCAAGCAGACCTGGCCCCTTCTCCCGTGGCTTCCCC GTTCTCCCCCACATGACCCCGAATGACAAACCTCATCCACAACGTCCTGCTCCGGGCAGT CCCGGGAGGGTCCCGCCGGCAGAGGTGAACGGGTCCACTTCTCCCACCCGCTTAGTGATA GTGTGTTCCTGACTCGGAGTGTGGCGAGGTAAAAAAAGACCAAGCAGATCCAGGAAAATG GGGAAAGAGCTACTGGCCCTTGAAGGATGCCTTTTCTTTTCCTTTTGTTAGGATATCAAA GCACTCCAAAGAGCGAAATATTTCATGTTCAGGATTTTCCGAGTGATTTTTTTTATGTGA CCTAAAGGTCCACCTAGAAAATGTTCACTTGTCTGGGGAGAATGCGCCCCACAGAGGAAA CTCTGGCCTGGGGTGGGAAGATTTGGTCCCTTTACACCCCCTCCCCGGGAAAGGAGCTCC TTCTTCAGTAGGAAGCTCCTGGGCAAAGTGATGCACGCCCACCCCAGCTTCGCAGCCTAG GCACTCCCATTTCTGGGGTTCCCTTACCAACCATCTTGCATTTAAACTTCTAGACTGCCA TTACTAAGAGAGGCTGGTTCCAGAGGATGCATCTGGCTCACCGGGTGTTCCGAAACCAAA GAAGAAACTTCGCCTTATCAGCTTCATACTTCATGAAATCCTGGGTTTTCTTAACCATCT TTTCCTCATTTTCAATGGTTTAACATATAATTTCTTTAAATAAAACCCTTAAAATCTGCT AAA OMIM ID 182590