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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for TFF3 (Homo sapiens) (Information is obtained from NCBI Gene database)

Entrez gene ID 7033 Official gene symbol TFF3 Full name trefoil factor 3 (intestinal) Aliases ,ITF,P1B,TFI, Gene summary Members of the trefoil family are characterized by having at least one copy of the trefoil motif, a 40-amino acid domain that contains three conserved disulfides. They are stable secretory proteins expressed in gastrointestinal mucosa. Their functions are not defined, but they may protect the mucosa from insults, stabilize the mucus layer and affect healing of the epithelium. This gene is expressed in goblet cells of the intestines and colon. This gene and two other related trefoil family member genes are found in a cluster on chromosome 21. [provided by RefSeq] Location Chromosome: 21   Locus: 21q22.3 Gene position 43735706 - 43731777  Map Viewer Gene orientation minus Gene size 3930 bp Gene sequence >TFF3:complement(726218..730147):Length=3930 GCCAAAACAGTGGGGGCTGAACTGACCTCTCCCCTTTGGGAGAGAAAAACTGTCTGGGAG CTTGACAAAGGCATGCAGGAGAGAACAGGAGCAGCCACAGCCAGGAGGGAGAGCCTTCCC CAAGCAAACAATCCAGAGCAGCTGTGCAAACAACGGTGCATAAATGAGGCCTCCTGGACC ATGAAGCGAGTCCTGAGCTGCGTCCCGGAGCCCACGGTGGTCATGGCTGCCAGAGCGCTC TGCATGCTGGGGCTGGTCCTGGCCTTGCTGTCCTCCAGCTCTGCTGAGGAGTACGTGGGC CTGTGTGAGTACTGCCCTGACTGCCCCGGTGGCAGGGTGGGCGTGAAGGGAAGGGATCCA GGATAAGGGGGGATTCTGCATTCATTTAATAATGGCCACCTGTCACATATACACTTTTTC CTGCGCTAGCCCTTTGAAGTGGGTCTTTATTGTCCCCATTTCACAGACAAGGAAACCGAG GCTCAGAGAAAGTTAACAACTTATCCAAGGCAGCCCTGCCCAGTCTGTGTTGAAATCAGG GTTTGAGCCTGAGCCCATCCCCTATGACCCCATAGCCATCTTTGCTGGAGATTTCTAAAT TACAATATAGGTCTTTATGCATTGTTCCACATTTACAAAGAAAAAGGAAAGATGCAGGAG AAAAACCCTGACTTCAGAACACTGTCAATACCGGCAGGCACAAGGTTCATTTAGCCATTG CATAGCAACCCTGCCATGGGGTGTGGCTGCTCCATTAACCCAAGTTTGAAGGAATGAGGG CATGGCTTTTATCTGGGTGTCTTCTGAGCAGGGTCAAAGGCAGTGGTTCCCGAACTTGCA GCCCATTAGAATCACCTGGAGAGCTTTAAAAATCCTAATGCTTGGGGCACACCAGTTACA TCAGGGCATCTCCAGGCAAGATCCAGGCCTCAGCTGTTTTGTTTTGAGATAGCCTTGCTT TGTCACTCACTGCTGGAGTGCAGTGGCACAATCTCAGCTCACTGCAACCTCCGCCTCCTG GGTTCAAGCAATTCTTGTGCCTCGGCTTCAAGTAGCTGGGATTACAGGCATGCACCACCA TGCCCAGCTAATTTTTTGGATTTTTAGTAGAGATGGAGTTTCGCTATGTTGGCCAAGCTG GTCTCAAACTCCTGGCCTCAAGTGATCCTCCTGCCTTGGCCTCCCAAAGTGCTGGAATTA CAGGTGTAAGCCACCATGCCCAGCCAACGTCAGTCATTTTTAAAGCTCTGCAGCTGATTC CAGTGTGAGCGAAGTTTGGATGCCAGGAGGATAAGCAATTACGGACTGGGAGCAAGAGAA GGGAATGTAAGACACTGCACGTGATTGCCATTTTCCTAAGGAAATACTCAGTTCGTTAAT GAAACGCAGTGAACTTCTGCTGCACATACAGACATAGAGGCTTGCCTGAAACATGAAAAT ATTGGGGACTGAAGGATGTCCCGGGAGGGTGGGACATGCTCAACAATTCAGGAAGGGGAG ATGCAGAAAAAAGTGAAAAGCAGGCAGCATGCGTTGCAATGATCTCTATGGCGTGTGCCT CTCCTGTCACGGTTTTCATTTAAAACAAAGGGGCAAGGTTTTGTTGGTCAAACAATGAAG GGTAACTTTGTTTCTGGGTTCAAGGGACCCCAGATTCCCCAGGGGTTCCTGCCAGCTGGA AGGTACCCAGGTCCGTATGTGACTTCCCGAGAAGGTGATAAGAGCGTGCCAAGGAGAAAG ACACTTAGGCAAATGGCCAGAGTCCCCGAGCTGAGCATTTAACAGACTGCCTCTCTTTAA ATATTCACAGGGAAAGTGCATCTTCCTAAGGGCGAGGGTTTCAGCAGTGGTTGAACTCGG CGGGGTGGGGCGGAGCGGGAGGATGCAAACTTGCAAAGTGAAGCAAACACACTCACCGCA GCCCAGCAAGGGCTCTGGCAGCTGACAGGGCTTTGTCTGGGACAGCTGCAAACCAGTGTG CCGTGCCAGCCAAGGACAGGGTGGACTGCGGCTACCCCCATGTCACCCCCAAGGAGTGCA ACAACCGGGGCTGCTGCTTTGACTCCAGGATCCCTGGAGTGCCTTGGTGTTTCAAGCCCC TGCAGGAAGCAGGTAAGGCCCCAGTGGCATCGTGGTCTGGGCCCAGCCCCATAAGGCAGG GGGTCTCAGGGCCTCCCTGTCCTTTCTGGGCTGGAGATGGAGGCACAAGGACCCCAGGAA GCCACACACACACACCTGTTCCAAGGCCTCAGAGCAGAGGCTTCACACTTAGGGCAGCCA TGGCCAGGGGCTGTCCTCTTCTGTCCCCTTTATGTAAAACATAAAAGCAATTGTTTCAAA AAGGTGTTCAAAATGATGGCATCGCATAGAGGGAACTGATTTAGTAACTATTCTTGAGAG AAGTGGAAACGCATAGGTGTGGAAAGCCGGGCCGACTTTTGGGCTGTTTTTGCAAATCGG CCCCCCAGAGTCTTGTCATTTGTGGCATCCCCTACACAGACGGCAGGCGGTCCCAGCCCT AGACGTCAGGCCTCGGTGCCACACCCCACCTCCCCCACTCTGCCCCCCACAAGGGTCATC TCCTCTCCCTCTCTCTGCCGTGGTGGAGGGCAGGTGCAGGGCAACCACCCTGGGGGTTCC CTCCCCAGGGGCGGAGAGCCTGCGTGCTGTGCGGGTAACAGATGGCCCTGCACACGGGTT TGCCACCCTGGCTCCACCAGGCTTAGCTGCCCCACATCGTGGGTGGGGCGATTGGCTATA AGCCATCTGCCATGTCCAAGTGCCAGCTCAGCCCCCACGAAGGCCGCACCTGCGTGAGGT ACCTTCCTGGAACCAGCATCCAGAGGGGCCTCTCTTGCCCTTTGTCCTAGGGTGAAATGC GGGAGGCTGAGTCCTGCTGGCCCCGGCTCCCTGATCAATGATGGGCCCCTGCCCAGGGCC TCCCTTCACCCTCCCCAGCAAGTCCAGGGTAGGGGTGGGGGTGGGGGTCCAGAGAAGGCC AGGAGAGAGAGGGGTCTGGCTACTGTCCACTGCCGGTCCTGTTCCTTCAGCTCCACTGGA ACTACACTCTCCTCTGAGTGCCAGCCATGGCCCTGCCAAGGCCCATCTCGCTTGTTATCT GCCTGATCCCTGGGTCCCACTATCTTGCTTAGCAACCCGAGGTGGGAATCTTGGCTATTC CCCCATGTGGTGGGGACTCAACACTCCCCGGTGACTCTGGGGAGGAGGCAGCACTAGGTG CTGGCCTTGGAGCCTGCCCTGACCTTGGGAAGCTGGGCAGCGTGGGTGGAGAGAGACTGC TCACACAAGCCTTTGCTCTGTTTGCAGAATGCACCTTCTGAGGCACCTCCAGCTGCCCCC GGCCGGGGGATGCGAGGCTCGGAGCACCCTTGCCCGGCTGTGATTGCTGCCAGGCACTGT TCATCTCAGCTTTTCTGTCCCTTTGCTCCCGGCAAGCGCTTCTGCTGAAAGTTCATATCT GGAGCCTGATGTCTTAACGAATAAAGGTCCCATGCTCCACCCGAGGACAGTTCTTCGTGC CTGAGACTTTCTGAGGTTGTGCTTTATTTCTGCTGCGTCGTGGGAGAGGGCGGGAGGGTG TCAGGGGAGAGTCTGCCCAGGCCTCAAGGGCAGGAAAAGACTCCCTAAGGAGCTGCAGTG CATGCAAGGATATTTTGAATCCAGACTGGCACCCACGTCACAGGAAAGCCTAGGAACACT GTAAGTGCCGCTTCCTCGGGAAAGCAGAAAAAATACATTTCAGGTAGAAGTTTTCAAAAA TCACAAGTCTTTCTTGGTGAAGACAGCAAGCCAATAAAACTGTCTTCCAAAGTGGTCCTT TATTTCACAACCACTCTCGCTACTGTTCAATACTTGTACTATTCCTGGGTTTTGTTTCTT TGTACAGTAAACATTATGAACAAACAGGCA OMIM ID 600633